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Status: Bibliographieeintrag

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Verfasst von:Stolzenburg, Jens-Uwe [VerfasserIn]   i
 Holze, Sigrun [VerfasserIn]   i
 Arthanareeswaran, Vinodh-Kumar-Adithyaa [VerfasserIn]   i
 Neuhaus, Petra [VerfasserIn]   i
 Do, Hoang Minh [VerfasserIn]   i
 Haney, Caelán Max [VerfasserIn]   i
 Dietel, Anja [VerfasserIn]   i
 Truss, Michael C. [VerfasserIn]   i
 Stützel, Karin Daniela [VerfasserIn]   i
 Teber, Dogu [VerfasserIn]   i
 Hohenfellner, Markus [VerfasserIn]   i
 Rabenalt, Robert [VerfasserIn]   i
 Albers, Peter [VerfasserIn]   i
 Mende, Meinhard [VerfasserIn]   i
Titel:Robotic-assisted versus laparoscopic radical prostatectomy
Titelzusatz:12-month outcomes of the multicentre randomised controlled LAP-01 trial
Verf.angabe:Jens-Uwe Stolzenburg, Sigrun Holze, Vinodh-Kumar-Adithyaa Arthanareeswaran, Petra Neuhaus, Hoang Minh Do, Caelán Max Haney, Anja Dietel, Michael C. Truss, Karin Daniela Stützel, Dogu Teber, Markus Hohenfellner, Robert Rabenalt, Peter Albers, Meinhard Mende
E-Jahr:2022
Jahr:23 February 2022
Umfang:8 S.
Illustrationen:Illustrationen
Fussnoten:Gesehen am 25.10.2023
Titel Quelle:Enthalten in: European urology focus
Ort Quelle:Amsterdam : Elsevier, 2015
Jahr Quelle:2022
Band/Heft Quelle:8(2022), 6, Seite 1583-1590
ISSN Quelle:2405-4569
Abstract:BACKGROUND: Recently, our LAP-01 trial demonstrated superiority of robotic-assisted laparoscopic radical prostatectomy (RARP) over conventional laparoscopic radical prostatectomy (LRP) with respect to continence at 3 mo. OBJECTIVE: To compare the continence, potency, and oncological outcomes between RARP and LRP in the 12-mo follow-up. DESIGN, SETTING, AND PARTICIPANTS: In this multicentre, randomised, patient-blinded controlled trial, patients referred for radical prostatectomy to four hospitals in Germany were randomly assigned (3:1) to undergo either RARP or LRP. OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Continence was assessed as a patient-reported outcome through validated questionnaires. Secondary endpoints included potency and oncological outcomes. Data were statistically analysed by bivariate tests and multivariable models. RESULTS AND LIMITATIONS: At 12 mo, follow-up data were available for 701 of 782 patients. Continence at 6 and 12 mo after surgery was better in RARP patients, however no longer statistically significant (p = 0.068 and 0.38, respectively). Patients who were potent at baseline and underwent nerve-sparing surgery reported significantly higher potency after RARP, as defined by the capability to maintain an erection sufficient for intercourse at 3 (p = 0.005), 6 (p = 0.018), and 12 mo (p = 0.013). There were no statistically significant differences in oncological outcomes at 12 mo. It is a limitation that the influence of different anastomotic techniques was not investigated in this study. CONCLUSIONS: Both LRP and RARP offer a high standard of therapy for prostate cancer patients. However, robotic assistance offers better functional outcomes in specific areas such as potency and early continence in patients who are eligible for nerve-sparing RP. PATIENT SUMMARY: We compared outcomes 12 mo after radical prostatectomy between robotic-assisted and conventional laparoscopy. Both methods were equivalent with respect to oncological outcomes. Better recovery of continence in patients with robotic-assisted surgery, which was observed at 3 mo, blurred up to 12 mo. A benefit of robotic-assisted surgery was also observed in potency.
DOI:doi:10.1016/j.euf.2022.02.002
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1016/j.euf.2022.02.002
 Volltext: https://www.sciencedirect.com/science/article/pii/S2405456922000487
 DOI: https://doi.org/10.1016/j.euf.2022.02.002
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:continence
 Germany
 humans
 laparoscopic prostatectomy
 multicentre randomised trial
 potency
 prostate cancer
 prostatectomy
 robotic surgical procedures
 robotic-assisted prostatectomy
 robotics
K10plus-PPN:1867632853
Verknüpfungen:→ Zeitschrift

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