Distribution and prognostic impact of coronary artery disease and nonischemic cardiomyopathies in patients with electrical storm

• Verfasst von: Müller, Julian [VerfasserIn]
• Verfasst von: Behnes, Michael [VerfasserIn]
• Verfasst von: Ellguth, Dominik [VerfasserIn]
• Verfasst von: Schupp, Tobias [VerfasserIn]
• Verfasst von: Taton, Gabriel [VerfasserIn]
• Verfasst von: Reiser, Linda [VerfasserIn]
• Verfasst von: Engelke, Niko [VerfasserIn]
• Verfasst von: Borggrefe, Martin [VerfasserIn]
• Verfasst von: Reichelt, Thomas [VerfasserIn]
• Verfasst von: Kern-Bollow, Armin [VerfasserIn]
• Verfasst von: Kim, Seung‑Hyun [VerfasserIn]
• Verfasst von: Barth, Christian [VerfasserIn]
• Verfasst von: Weidner, Kathrin [VerfasserIn]
• Verfasst von: El-Battrawy, Ibrahim [VerfasserIn]
• Verfasst von: Ansari, Uzair [VerfasserIn]
• Verfasst von: Akın, Muharrem [VerfasserIn]
• Verfasst von: Große Meininghaus, Dirk [VerfasserIn]
• Verfasst von: Mashayekhi, Kambis [VerfasserIn]
• Verfasst von: Akın, Ibrahim [VerfasserIn]
• Titel: Distribution and prognostic impact of coronary artery disease and nonischemic cardiomyopathies in patients with electrical storm
• Verf.angabe: Julian Müller, Michael Behnes, Dominik Ellguth, Tobias Schupp, Gabriel Taton, Linda Reiser, Niko Engelke, Martin Borggrefe, Thomas Reichelt, Armin Bollow, Seung-Hyun Kim, Christian Barth, Kathrin Weidner, Ibrahim-El- Battrawy, Uzair Ansari, Muharrem Akin, Dirk Große Meininghaus, Kambis Mashayekhi, Ibrahim Akin
• E-Jahr: 2022
• Jahr: August 2022
• Umfang: 10 S.
• Fussnoten: Gesehen am 30.10.2023
• Titel Quelle: Enthalten in: Coronary artery disease
• Ort Quelle: London : Lippincott Williams & Wilkins, 1990
• Jahr Quelle: 2022
• Band/Heft Quelle: 33(2022), 5, Seite 403-412
• ISSN Quelle: 1473-5830
• DOI: doi:10.1097/MCA.0000000000001140
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1868787567

Abstract

Background: he distribution and prognostic impact of coronary artery disease (CAD) in ES are still under debate. Methods: Consecutive ES patients with implantable cardioverter-defibrillator (ICD) were included retrospectively from 2002 to 2016. Three analyses were applied to characterize ES patients: (a) ES patients without CAD (non-CAD), (b) ES patients with CAD (CAD), and (c) diagnostic findings assessed by coronary angiography (CA) at the time of ES (immediate CA). CAD was compared with non-CAD ES patients, and progressive CAD was compared with stable CAD ES patients. The primary endpoint was all-cause mortality at 2.5 years. Secondary endpoints were the composite endpoint of first recurrent ventricular tachyarrhythmias and appropriate ICD therapies, and recurrence of ES (ES-R) at 2.5 years.Results: Within a total of 87 consecutive ES patients. CAD was present in more than two-thirds (67%). However, only 52% patients underwent immediate CA at the time of ES. Here, 84% had CAD, of which 39% revealed progressive CAD with the need of target vessel revascularization (TVR) or cardiac transplantation (n = 1). At long-term follow-up, neither the presence (or absence) of CAD (41% vs. 34%; log rank P = 0.708) nor of progressive CAD (33% vs. 26%; log rank P = 0.372) was associated with all-cause mortality at 2.5 years, and further secondary endpoints including the composite of recurrent ventricular tachyarrhythmias plus appropriate ICD therapies, or ES-R. Conclusion: In ES patients, CAD was more common than non-CAD-related cardiac diseases, accompanied by an underinvestigated rate of CA despite increasing rates of progressive CAD. CAD had no prognostic impact in ES.