| Online-Ressource |
Verfasst von: | Alizadeh, Leona Soraja [VerfasserIn]  |
| Koch, Vitali [VerfasserIn]  |
| Vogl, Thomas J. [VerfasserIn]  |
| Yel, Ibrahim [VerfasserIn]  |
| Gruenewald, Leon [VerfasserIn]  |
| Albrecht, Moritz H. [VerfasserIn]  |
| Herrmann, Eva [VerfasserIn]  |
| Knebel Doeberitz, Philipp L. von [VerfasserIn]  |
| Booz, Christian [VerfasserIn]  |
Titel: | Value of latest-generation cone-beam computed tomography for post lipiodol-embolization imaging in hepatic transarterial chemoembolization in comparison with multi-detector computed tomography |
Titelzusatz: | original investigation |
Verf.angabe: | Leona S. Alizadeh, Vitali Koch, Thomas J. Vogl, Ibrahim Yel, Leon Gruenewald, Moritz H. Albrecht, Eva Herrmann, Philipp L. von Knebel-Doeberitz, Christian Booz |
E-Jahr: | 2022 |
Jahr: | July 2022 |
Umfang: | 10 S. |
Fussnoten: | Online verfügbar: 28 September 2021, Artikelversion: 26 May 2022 ; Gesehen am 14.11.2023 |
Titel Quelle: | Enthalten in: Academic radiology |
Ort Quelle: | Philadelphia, PA [u.a.] : Elsevier, 1994 |
Jahr Quelle: | 2022 |
Band/Heft Quelle: | 29(2022), 7 vom: Juli, Seite e109-e118 |
ISSN Quelle: | 1878-4046 |
Abstract: | Rationale and Objectives - To evaluate image quality, radiation dose (phantom study) and tumor volumetry of intraprocedural cone-beam computed tomography (CBCT) compared to postprocedural multidetector computed tomography (MDCT) in patients undergoing hepatic conventional transarterial chemoembolization (cTACE). - Materials and Methods - One hundred fourteen patients (64/50 female/male; mean age, 57 ± 14 years) who had undergone cTACE including intraprocedural-CBCT and postprocedural-MDCT were retrospectively enrolled. Subjective image quality (IQ) and suitability for assessing Lipiodol distribution were compared using 4-point Likert scales; additionally, lesion to liver contrast (LLC) and contrast-to-noise-ratio (CNR) were compared. Tumor volumes were measured semi-automatically and compared to magnetic resonance imaging (MRI). Effective doses were measured using an anthropomorphic phantom. - Results - The suitability of CBCT for assessing Lipiodol distribution during cTACE was comparable to MDCT (mean score, 3.2 ± 0.6) and CBCT (3.4 ± 1.0, p = 0.29). Subjective overall IQ was rated with a mean score of 3.2 ± 0.7 (κ = 0.66) in CBCT and 3.1 ± 0.4 (κ = 0.57, p = 0.15) in MDCT. Evaluation of LLC showed significant differences between CBCT and MDCT (mean scores 3.6 ± 1.2 and 2.6 ± 1.5, respectively). CNR analysis demonstrated comparable mean values for CBCT and MDCT (3.5 ± 1.3 vs. 3.4 ± 1.8, p = 0.31). No significant differences were found regarding tumor volumetry (mean volumes: CBCT, 27.0 ± 17.4 mm3; MDCT: 26.8 ± 16.0 mm3; p = 0.66) in comparison to T2-weighted MRI (25.9 ± 17.6 mm3). Effective doses were 3.2 ± 0.6 mSv (CBCT) and 2.5 ± 0.3 mSv (MDCT) (p < 0.001). No cTACE-related complications (bleeding, non-target embolization) were missed on intraprocedural CBCT in comparison to postprocedural MDCT. - Conclusion - Latest-generation intraprocedural CBCT provides suitable assessment of Lipiodol distribution and similar image quality compared to MDCT while allowing for robust volumetric tumor measurements and immediate complication control by visualizing non-target embolization and hematoma. Therefore, it may improve patient safety and outcome as well as clinical workflow compared to postprocedural MDCT in hepatic cTACE in certain cases. |
DOI: | doi:10.1016/j.acra.2021.07.029 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1016/j.acra.2021.07.029 |
| Volltext: https://www.sciencedirect.com/science/article/pii/S1076633221003706 |
| DOI: https://doi.org/10.1016/j.acra.2021.07.029 |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | Chemoembolization |
| Cone-Beam Computed Tomography |
| Imaging |
| Multidetector Computed Tomography |
| Phantoms |
| Radiation Dose |
| Therapeutic |
K10plus-PPN: | 1870208528 |
Verknüpfungen: | → Zeitschrift |
Value of latest-generation cone-beam computed tomography for post lipiodol-embolization imaging in hepatic transarterial chemoembolization in comparison with multi-detector computed tomography / Alizadeh, Leona Soraja [VerfasserIn]; July 2022 (Online-Ressource)