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| Verfasst von: | Buitelaar, Jan K. [VerfasserIn]  |
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| | Bölte, Sven [VerfasserIn] |
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| | Brandeis, Daniel [VerfasserIn] |
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| | Caye, Arthur [VerfasserIn] |
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| | Christmann, Nina [VerfasserIn] |
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| | Cortese, Samuele [VerfasserIn] |
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| | Coghill, David [VerfasserIn] |
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| | Faraone, Stephen V. [VerfasserIn] |
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| | Franke, Barbara [VerfasserIn] |
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| | Gleitz, Markus [VerfasserIn] |
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| | Greven, Corina U. [VerfasserIn] |
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| | Kooij, Sandra [VerfasserIn] |
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| | Leffa, Douglas Teixeira [VerfasserIn] |
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| | Rommelse, Nanda [VerfasserIn] |
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| | Newcorn, Jeffrey H. [VerfasserIn] |
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| | Polanczyk, Guilherme V. [VerfasserIn] |
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| | Rohde, Luis Augusto [VerfasserIn] |
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| | Simonoff, Emily [VerfasserIn] |
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| | Stein, Mark [VerfasserIn] |
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| | Vitiello, Benedetto [VerfasserIn] |
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| | Yazgan, Yanki [VerfasserIn] |
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| | Roesler, Michael [VerfasserIn] |
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| | Doepfner, Manfred [VerfasserIn] |
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| | Banaschewski, Tobias [VerfasserIn] |
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| Titel: | Toward precision medicine in ADHD |
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| Verf.angabe: | Jan Buitelaar, Sven Bölte, Daniel Brandeis, Arthur Caye, Nina Christmann, Samuele Cortese, David Coghill, Stephen V. Faraone, Barbara Franke, Markus Gleitz, Corina U. Greven, Sandra Kooij, Douglas Teixeira Leffa, Nanda Rommelse, Jeffrey H. Newcorn, Guilherme V. Polanczyk, Luis Augusto Rohde, Emily Simonoff, Mark Stein, Benedetto Vitiello, Yanki Yazgan, Michael Roesler, Manfred Doepfner and Tobias Banaschewski |
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| E-Jahr: | 2022 |
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| Jahr: | 06 July 2022 |
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| Umfang: | 25 S. |
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| Fussnoten: | Gesehen am 20.11.2023 |
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| Titel Quelle: | Enthalten in: Frontiers in behavioral neuroscience |
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| Ort Quelle: | Lausanne : Frontiers Research Foundation, 2007 |
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| Jahr Quelle: | 2022 |
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| Band/Heft Quelle: | 16(2022), Artikel-ID 900981, Seite 1-25 |
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| ISSN Quelle: | 1662-5153 |
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| Abstract: | Attention-Deficit Hyperactivity Disorder (ADHD) is a complex and heterogeneous neurodevelopmental condition for which curative treatments are lacking. Whilst pharmacological treatments are generally effective and safe, there is considerable inter-individual variability among patients regarding treatment response, required dose, and tolerability. Many of the non-pharmacological treatments, which are preferred to drug-treatment by some patients, either lack efficacy for core symptoms or are associated with small effect sizes. No evidence-based decision tools are currently available to allocate pharmacological or psychosocial treatments based on the patient's clinical, environmental, cognitive, genetic, or biological characteristics. We systematically reviewed potential biomarkers that may help in diagnosing ADHD and/or stratifying ADHD into more homogeneous subgroups and/or predict clinical course, treatment response, and long-term outcome across the lifespan. Most work involved exploratory studies with cognitive, actigraphic and EEG diagnostic markers to predict ADHD, along with relatively few studies exploring markers to subtype ADHD and predict response to treatment. There is a critical need for multisite prospective carefully designed experimentally controlled or observational studies to identify biomarkers that index inter-individual variability and/or predict treatment response. |
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| DOI: | doi:10.3389/fnbeh.2022.900981 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: https://doi.org/10.3389/fnbeh.2022.900981 |
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| | kostenfrei: Volltext: https://www.frontiersin.org/articles/10.3389/fnbeh.2022.900981 |
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| | DOI: https://doi.org/10.3389/fnbeh.2022.900981 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| K10plus-PPN: | 1870638573 |
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| Verknüpfungen: | → Zeitschrift |
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Toward precision medicine in ADHD / Buitelaar, Jan K. [VerfasserIn]; 06 July 2022 (Online-Ressource)
