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Status: Bibliographieeintrag

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Verfasst von:Moazamian, Dina [VerfasserIn]   i
 Athertya, Jiyo S. [VerfasserIn]   i
 Dwek, Sophia [VerfasserIn]   i
 Lombardi, Alecio F. [VerfasserIn]   i
 Mohammadi, Hamidreza Shaterian [VerfasserIn]   i
 Sedaghat, Sam [VerfasserIn]   i
 Jang, Hyungseok [VerfasserIn]   i
 Ma, Yajun [VerfasserIn]   i
 Chung, Christine B. [VerfasserIn]   i
 Du, Jiang [VerfasserIn]   i
 Jerban, Saeed [VerfasserIn]   i
 Chang, Eric Y. [VerfasserIn]   i
Titel:Achilles tendon and enthesis assessment using ultrashort echo time magnetic resonance imaging (UTE-MRI) T1 and magnetization transfer (MT) modeling in psoriatic arthritis
Verf.angabe:Dina Moazamian, Jiyo S. Athertya, Sophia Dwek, Alecio F. Lombardi, Hamidreza Shaterian Mohammadi, Sam Sedaghat, Hyungseok Jang, Yajun Ma, Christine B. Chung, Jiang Du, Saeed Jerban, Eric Y. Chang
Jahr:2023
Umfang:9 S.
Illustrationen:Illustrationen
Fussnoten:Online veröffentlicht: 23. September 2023 ; Gesehen am 28.11.2023
Titel Quelle:Enthalten in: NMR in biomedicine
Ort Quelle:New York, NY : Wiley, 1988
Jahr Quelle:2023
Band/Heft Quelle:(2023) online ahead of print
ISSN Quelle:1099-1492
Abstract:The purpose of this study is to investigate the use of ultrashort echo time (UTE) magnetic resonance imaging (MRI) techniques (T1 and magnetization transfer [MT] modeling) for imaging of the Achilles tendons and entheses in patients with psoriatic arthritis (PsA) compared with asymptomatic volunteers. The heels of twenty-six PsA patients (age 59 ± 15 years, 41% female) and twenty-seven asymptomatic volunteers (age 33 ± 11 years, 47% female) were scanned in the sagittal plane with UTE-T1 and UTE-MT modeling sequences on a 3-T clinical scanner. UTE-T1 and macromolecular proton fraction (MMF; the main outcome of MT modeling) were calculated in the tensile portions of the Achilles tendon and at the enthesis (close to the calcaneus bone). Mann-Whitney-U tests were used to examine statistically significant differences between the two cohorts. UTE-T1 in the entheses was significantly higher for the PsA group compared with the asymptomatic group (967 ± 145 vs. 872 ± 133 ms, p < 0.01). UTE-T1 in the tendons was also significantly higher for the PsA group (950 ± 145 vs. 850 ± 138 ms, p < 0.01). MMF in the entheses was significantly lower in the PsA group compared with the asymptomatic group (15% ± 3% vs. 18% ± 3%, p < 0.01). MMF in the tendons was also significantly lower in the PsA group compared with the asymptomatic group (17% ± 4% vs. 20% ± 5%, p < 0.01). Percentage differences in MMF between the asymptomatic and PsA groups (−16.6% and −15.0% for the enthesis and tendon, respectively) were higher than the T1 differences (10.8% and 11.7% for the enthesis and tendon, respectively). The results suggest higher T1 and lower MMF in the Achilles tendons and entheses in PsA patients compared with the asymptomatic group. This study highlights the potential of UTE-T1 and UTE-MT modeling for quantitative evaluation of entheses and tendons in PsA patients.
DOI:doi:10.1002/nbm.5040
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1002/nbm.5040
 Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/nbm.5040
 DOI: https://doi.org/10.1002/nbm.5040
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:Achilles tendon
 enthesis
 MRI
 Psoriatic Arthritis
 UTE-MRI
K10plus-PPN:1871479487
Verknüpfungen:→ Zeitschrift

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