Photon-counting computed tomography of coronary and peripheral artery stents

• Verfasst von: Stein, Thomas [VerfasserIn]
• Verfasst von: Taron, Jana [VerfasserIn]
• Verfasst von: Verloh, Niklas [VerfasserIn]
• Verfasst von: Doppler, Michael [VerfasserIn]
• Verfasst von: Rau, Alexander [VerfasserIn]
• Verfasst von: Hagar, Muhammad Taha [VerfasserIn]
• Verfasst von: Faby, Sebastian [VerfasserIn]
• Verfasst von: Baltas, Dimos [VerfasserIn]
• Verfasst von: Westermann, Dirk [VerfasserIn]
• Verfasst von: Ayx, Isabelle [VerfasserIn]
• Verfasst von: Schönberg, Stefan [VerfasserIn]
• Verfasst von: Nikolaou, Konstantin [VerfasserIn]
• Verfasst von: Schlett, Christopher L. [VerfasserIn]
• Verfasst von: Bamberg, Fabian [VerfasserIn]
• Verfasst von: Weiss, Jakob [VerfasserIn]
• Titel: Photon-counting computed tomography of coronary and peripheral artery stents
• Titelzusatz: a phantom study
• Verf.angabe: Thomas Stein, Jana Taron, Niklas Verloh, Michael Doppler, Alexander Rau, Muhammad Taha Hagar, Sebastian Faby, Dimos Baltas, Dirk Westermann, Isabelle Ayx, Stefan O. Schönberg, Konstantin Nikolaou, Christopher L. Schlett, Fabian Bamberg & Jakob Weiss
• E-Jahr: 2023
• Jahr: 08 September 2023
• Umfang: 11 S.
• Illustrationen: Illustrationen
• Fussnoten: Online veröffentlicht: 08. September 2023 ; Gesehen am 06.12.2023
• Titel Quelle: Enthalten in: Scientific reports
• Ort Quelle: [London] : Springer Nature, 2011
• Jahr Quelle: 2023
• Band/Heft Quelle: 13(2023), Artikel-ID 14806, Seite 1-11
• ISSN Quelle: 2045-2322
• DOI: doi:10.1038/s41598-023-41854-3
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Anatomy
• Sach-SW: Cardiology
• Sach-SW: Health care
• K10plus-PPN: 1872131549

Abstract

Accurate small vessel stent visualization using CT remains challenging. Photon-counting CT (PCD-CT) may help to overcome this issue. We systematically investigate PCD-CT impact on small vessel stent assessment compared to energy-integrating-CT (EID). 12 water-contrast agent filled stents (3.0-8 mm) were scanned with patient-equivalent phantom using clinical PCD-CT and EID-CT. Images were reconstructed using dedicated vascular kernels. Subjective image quality was evaluated by 5 radiologists independently (5-point Likert-scale; 5 = excellent). Objective image quality was evaluated by calculating multi-row intensity profiles including edge rise slope (ERS) and coefficient-of-variation (CV). Highest overall reading scores were found for PCD-CT-Bv56 (3.6[3.3-4.3]). In pairwise comparison, differences were significant for PCD-CT-Bv56 vs. EID-CT-Bv40 (p ≤ 0.04), for sharpness and blooming respectively (all p < 0.05). Highest diagnostic confidence was found for PCD-CT-Bv56 (p ≤ 0.2). ANOVA revealed a significant effect of kernel strength on ERS (p < 0.001). CV decreased with stronger PCD-CT kernels, reaching its lowest in PCD-CT-Bv56 and highest in EID-CT reconstruction (p ≤ 0.05). We are the first study to verify, by phantom setup adapted to real patient settings, PCD-CT with a sharp vascular kernel provides the most favorable image quality for small vessel stent imaging. PCD-CT may reduce the number of invasive coronary angiograms, however, more studies needed to apply our results in clinical practice.