Nano Drug Delivery for Cancer Therapy

• Titel: Nano Drug Delivery for Cancer Therapy
• Titelzusatz: Principles and Practices
• Mitwirkende: Khan, Firdos Alam [HerausgeberIn]
• Verf.angabe: edited by Firdos Alam Khan
• Ausgabe: 1st ed. 2023.
• Verlagsort: Singapore
• Verlagsort: Singapore
• Verlag: Springer Nature Singapore
• Verlag: Imprint: Springer
• E-Jahr: 2023
• Jahr: 2023.
• Jahr: 2023.
• Umfang: 1 Online-Ressource(XIII, 251 p. 1 illus.)
• ISBN: 978-981-9969-40-1
• DOI: doi:10.1007/978-981-99-6940-1
• Datenträger: Online-Ressource
• Sprache: eng
• Bibliogr. Hinweis: Erscheint auch als : Druck-Ausgabe
• Bibliogr. Hinweis: Erscheint auch als : Druck-Ausgabe
• Bibliogr. Hinweis: Erscheint auch als : Druck-Ausgabe
• K10plus-PPN: 1877501735
• K10plus-PPN:
  Universitätsbibliothek
• Lokale URL UB: Zum Volltext
• Lokale URL UB: Bibliothek der Medizinischen Fakultät Mannheim der Universität Heidelberg
• Bibliothek/Idn: UW / m4451597331
• Lokale URL Inst.: Zum Volltext

Abstract

Ch 1 Significance of nano-drug delivery in cancer therapy, application of nanoparticles in overcoming drug resistance, targeted therapy, and Immunotherapy -- Ch 2 Synthesis of different types, shapes, and sizes of nanocarriers using synthetic and biological approaches -- Ch 3 Synthesis of nanocarriers loaded with anti-cancer drugs by using functionalization or conjugations, encapsulation methods -- Ch 4 Nano-Drug Carriers for Chemotherapeutic Agents Delivery in Cancer Disease Treatment -- Ch 5 Testing Of Nanocarriers Loaded with Chemotherapeutic Agents in the Animal Models of Cancers – Preclinical Trials for Efficacy and Safety Profiling of Nanocarriers -- Ch 6 Testing Of Nanocarriers Loaded With Chemotherapeutic Agents In The Animal Models Of Cancers – Preclinical Trials For Efficacy And Safety Profiling Of Nanocarriers -- Ch 7 Nanocarriers-Based Products In The Market, Fda Approval, Commercialization Of Nanocarriers, and Global Market -- Ch 8 Limitations of Nanocarriers Such as Cell and Tissue Toxicity, Genotoxicity, Scale-Up of Nanomaterials -- Ch 9 Health And Environmental Hazards Associated With The Synthesis Of Nanomaterials-Respiratory Diseases, Government Regulations, Ethical Issues -- Ch 10 Future trends and innovation in nano drug delivery for cancer therapy, application of siRNA (nanoparticle-based RNA) therapy, Ultrasound linked nano-cancer therapeutics, and application of exosomes-based cancer therapy.

Abstract

This book discusses the various modes and methods of nano-based drug delivery in different types of cancers such as colon, breast, cervical, ovarian, and lung cancer. It reviews the significance of nano drug delivery in cancer therapy, the application of nanoparticles in overcoming drug resistance, targeted therapy, and immunotherapy. The book also covers topics related to the synthesis of different types, shapes, and sizes of nanocarriers using synthetic and biological approaches. Further, a chapter explores the synthesis of nanocarriers loaded with anti-cancer drugs by using functionalization or conjugations and encapsulation methods. The book also examines the nanocarriers as delivery vehicles for chemotherapeutic agents against cancers using in vitro and animal models of cancers, preclinical trials for efficacy, and safety profiling of nanocarriers. Finally, future trends and innovation in nano drug delivery for cancer therapy, application of siRNA (nanoparticle-based RNA) therapy, ultrasound-linked nano-cancer therapeutics, and application of exosome-based cancer therapy topics are discussed. Towards the end, the book examines the limitations of nanocarriers, including the cell and tissue toxicity, genotoxicity, and scale-up of nanomaterials, health and environmental hazards associated with nanoformulation synthesis, respiratory diseases, government regulations, and ethical issues.