| |  Online-Ressource |
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| Verfasst von: | Huang, Xu [VerfasserIn]  |
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| | Schlesiger, Magdalene [VerfasserIn] |
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| | Barriuso-Ortega, Isabel [VerfasserIn] |
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| | Leibold, Christian [VerfasserIn] |
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| | MacLaren, Duncan Archibald Allan [VerfasserIn] |
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| | Bieber, Nina [VerfasserIn] |
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| | Monyer, Hannah [VerfasserIn] |
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| Titel: | Distinct spatial maps and multiple object codes in the lateral entorhinal cortex |
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| Verf.angabe: | Xu Huang, Magdalene Isabell Schlesiger, Isabel Barriuso-Ortega, Christian Leibold, Duncan Archibald Allan MacLaren, Nina Bieber, and Hannah Monyer |
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| E-Jahr: | 2023 |
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| Jahr: | October 2023 |
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| Umfang: | 24 S. |
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| Fussnoten: | Online verfügbar: 20. Juli 2023, Dokumentversion: 4. Oktober 2023 ; Gesehen am 26.01.2024 |
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| Titel Quelle: | Enthalten in: Neuron |
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| Ort Quelle: | [Cambridge, Mass.] : Cell Press, 1988 |
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| Jahr Quelle: | 2023 |
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| Band/Heft Quelle: | 111(2023), 19 vom: Okt., Seite [1], 3068-3083, e1-e7 |
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| ISSN Quelle: | 1097-4199 |
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| Abstract: | The lateral entorhinal cortex (LEC) is a major cortical input area to the hippocampus, and it is crucial for associative object-place-context memories. An unresolved question is whether these associations are performed exclusively in the hippocampus or also upstream of it. Anatomical evidence suggests that the LEC processes both object and spatial information. We describe here a gradient of spatial selectivity along the antero-posterior axis of the LEC. We demonstrate that the LEC generates distinct spatial maps for different contexts that are independent of object coding and vice versa, thus providing evidence for pure spatial and pure object codes upstream of the hippocampus. While space and object coding occur by and large separately in the LEC, we identified neurons that encode for space and objects conjunctively. Together, these findings point to a scenario in which the LEC sustains both distinct space and object coding and associative space-object coding. |
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| DOI: | doi:10.1016/j.neuron.2023.06.020 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1016/j.neuron.2023.06.020 |
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| | Volltext: https://www.sciencedirect.com/science/article/pii/S0896627323004798 |
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| | DOI: https://doi.org/10.1016/j.neuron.2023.06.020 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | hippocampus |
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| | lateral entorhinal cortex |
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| | object coding |
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| | place cells |
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| | spatial coding |
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| K10plus-PPN: | 1879357992 |
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| Verknüpfungen: | → Zeitschrift |
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Distinct spatial maps and multiple object codes in the lateral entorhinal cortex / Huang, Xu [VerfasserIn]; October 2023 (Online-Ressource)
