| |  Online-Ressource |
|---|
| Verfasst von: | Zopfs, Malte [VerfasserIn]  |
|---|
| | Jindrová, Miroslava [VerfasserIn] |
|---|
| | Gurevitch, Guy [VerfasserIn] |
|---|
| | Keynan, Jackob N. [VerfasserIn] |
|---|
| | Hendler, Talma [VerfasserIn] |
|---|
| | Baumeister, Sarah [VerfasserIn] |
|---|
| | Aggensteiner, Pascal [VerfasserIn] |
|---|
| | Cornelisse, Sven [VerfasserIn] |
|---|
| | Brandeis, Daniel [VerfasserIn] |
|---|
| | Schmahl, Christian [VerfasserIn] |
|---|
| | Paret, Christian [VerfasserIn] |
|---|
| Titel: | Amygdala-related electrical fingerprint is modulated with neurofeedback training and correlates with deep-brain activation |
|---|
| Titelzusatz: | proof-of-concept in borderline personality disorder: original article |
|---|
| Verf.angabe: | Malte Zopfs, Miroslava Jindrová, Guy Gurevitch, Jackob N. Keynan, Talma Hendler, Sarah Baumeister, Pascal-M. Aggensteiner, Sven Cornelisse, Daniel Brandeis, Christian Schmahl and Christian Paret |
|---|
| E-Jahr: | 2023 |
|---|
| Jahr: | 22 December 2023 |
|---|
| Umfang: | 10 S. |
|---|
| Illustrationen: | Illustrationen |
|---|
| Fussnoten: | Gesehen am 15.02.2024 |
|---|
| Titel Quelle: | Enthalten in: Psychological medicine |
|---|
| Ort Quelle: | Cambridge : Cambridge Univ. Press, 1970 |
|---|
| Jahr Quelle: | 2023 |
|---|
| Band/Heft Quelle: | (2023), Seite 1-10 |
|---|
| ISSN Quelle: | 1469-8978 |
|---|
| Abstract: | Background: The modulation of brain circuits of emotion is a promising pathway to treat borderline personality disorder (BPD). Precise and scalable approaches have yet to be established. Two studies investigating the amygdala-related electrical fingerprint (Amyg-EFP) in BPD are presented: one study addressing the deep-brain correlates of Amyg-EFP, and a second study investigating neurofeedback (NF) as a means to improve brain self-regulation.MethodsStudy 1 combined electroencephalography (EEG) and simultaneous functional magnetic resonance imaging to investigate the replicability of Amyg-EFP-related brain activation found in the reference dataset (N = 24 healthy subjects, 8 female; re-analysis of published data) in the replication dataset (N = 16 female individuals with BPD). In the replication dataset, we additionally explored how the Amyg-EFP would map to neural circuits defined by the research domain criteria. Study 2 investigated a 10-session Amyg-EFP NF training in parallel to a 12-weeks residential dialectical behavior therapy (DBT) program. Fifteen patients with BPD completed the training, N = 15 matched patients served as DBT-only controls.ResultsStudy 1 replicated previous findings and showed significant amygdala blood oxygenation level dependent activation in a whole-brain regression analysis with the Amyg-EFP. Neurocircuitry activation (negative affect, salience, and cognitive control) was correlated with the Amyg-EFP signal. Study 2 showed Amyg-EFP modulation with NF training, but patients received reversed feedback for technical reasons, which limited interpretation of results.ConclusionsRecorded via scalp EEG, the Amyg-EFP picks up brain activation of high relevance for emotion. Administering Amyg-EFP NF in addition to standardized BPD treatment was shown to be feasible. Clinical utility remains to be investigated. |
|---|
| DOI: | doi:10.1017/S0033291723003549 |
|---|
| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1017/S0033291723003549 |
|---|
| | Volltext: https://www.cambridge.org/core/journals/psychological-medicine/article/amygdalarelated-electrical-fingerprint-is-modulat ... |
|---|
| | DOI: https://doi.org/10.1017/S0033291723003549 |
|---|
| Datenträger: | Online-Ressource |
|---|
| Sprache: | eng |
|---|
| Sach-SW: | Affective Lability Scale |
|---|
| | amygdala |
|---|
| | amygdala-related electrical fingerprint |
|---|
| | Beck's Depression Inventory |
|---|
| | blood oxygenation level dependent |
|---|
| | borderline personality disorder |
|---|
| | brain imaging data structure |
|---|
| | default-mode network |
|---|
| | dialectical behavior therapy |
|---|
| | dorsal anterior cingulate cortex |
|---|
| | dorsolateral prefrontal cortex |
|---|
| | EEG |
|---|
| | electro-oculogram |
|---|
| | electroencephalography |
|---|
| | emotion regulation |
|---|
| | fMRI |
|---|
| | functional magnetic resonance imaging |
|---|
| | general linear model |
|---|
| | interquartile range |
|---|
| | neurofeedback |
|---|
| | neuroimaging |
|---|
| | personal effect size |
|---|
| | post-traumatic stress disorder |
|---|
| | psychopathology |
|---|
| | silver/silver chloride |
|---|
| | State-Trait Anxiety Inventory |
|---|
| | Toronto alexithymia Scale |
|---|
| K10plus-PPN: | 1880829096 |
|---|
| Verknüpfungen: | → Zeitschrift |
|---|
Amygdala-related electrical fingerprint is modulated with neurofeedback training and correlates with deep-brain activation / Zopfs, Malte [VerfasserIn]; 22 December 2023 (Online-Ressource)
