Chronic alcohol consumption and COVID-19 infection risk

• Verfasst von: Friske, Marion [VerfasserIn]
• Verfasst von: Spanagel, Rainer [VerfasserIn]
• Titel: Chronic alcohol consumption and COVID-19 infection risk
• Titelzusatz: a narrative review
• Verf.angabe: Marion M Friske, Rainer Spanagel
• E-Jahr: 2023
• Jahr: April 2023
• Illustrationen: Illustrationen
• Fussnoten: Online veröffentlicht: 27. Februar 2023 ; Gesehen am 15.02.2024
• Titel Quelle: Enthalten in: Alcohol
• Ort Quelle: Hoboken, New Jersey : Wiley, 2023
• Jahr Quelle: 2023
• Band/Heft Quelle: 47(2023), 4, Seite 629-639
• ISSN Quelle: 2993-7175
• DOI: doi:10.1111/acer.15041
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: alcohol consumption
• Sach-SW: alcohol use disorder
• Sach-SW: COVID-19
• Sach-SW: COVID-19 infection risk
• K10plus-PPN: 1880833980

Abstract

During the COVID-19 pandemic, many potential risk groups have been identified, such as those with obesity, diabetes, preexisting organ injuries, and several other conditions. Smoking is the most reported substance use disorder linked to increased COVID-19 hospitalization rate and disease severity. In relation to smoking, we discuss the impairment of the innate and the adaptive immune systems as being among the main potential reasons for increased COVID-19 infection risk and severity. Chronic alcohol consumption and alcohol use disorder (AUD) also have a negative impact on the immune system, but when it comes to COVID-19 risk, they produce diverse outcomes. Some studies provide evidence that chronic alcohol consumption and AUD increase the risk of COVID-19 infection and severe disease progression, while others report reduced hospitalization and death rates. In this review, we summarize the current state of epidemiological and molecular data concerning alcohol consumption and AUD as risk factors for COVID-19 infection, hospitalization, and mortality.