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Verfasst von:Siegler, Benedikt Hermann [VerfasserIn]   i
 Dos Santos Pereira, Rui Pedro [VerfasserIn]   i
 Keßler, Jens [VerfasserIn]   i
 Wallwiener, Stephanie [VerfasserIn]   i
 Wallwiener, Markus [VerfasserIn]   i
 Larmann, Jan [VerfasserIn]   i
 Picardi, Susanne [VerfasserIn]   i
 Carr, Richard [VerfasserIn]   i
 Weigand, Markus A. [VerfasserIn]   i
 Oehler, Beatrice [VerfasserIn]   i
Titel:Intranasal lidocaine administration via mucosal atomization device
Titelzusatz:a simple and successful treatment for postdural puncture headache in obstetric patients
Verf.angabe:Benedikt Hermann Siegler, Rui Pedro dos Santos Pereira, Jens Keßler, Stephanie Wallwiener, Markus Wallwiener, Jan Larmann, Susanne Picardi, Richard Carr, Markus Alexander Weigand and Beatrice Oehler
E-Jahr:2023
Jahr:13 December 2023
Umfang:14 S.
Illustrationen:Illustrationen
Fussnoten:Gesehen am 23.02.2024
Titel Quelle:Enthalten in: Biomedicines
Ort Quelle:Basel : MDPI, 2013
Jahr Quelle:2023
Band/Heft Quelle:11(2023), 12, Artikel-ID 3296, Seite 1-14
ISSN Quelle:2227-9059
Abstract:(1) Background: Postdural puncture headache (PDPH) remains a serious complication in obstetric patients. While the epidural blood patch represents the current gold standard in therapy, a growing number of alternative measures are thought to be beneficial for clinical management. The purpose of this study was to retrospectively analyze the efficacy of intranasal lidocaine administration to treat PDPH in obstetrics at our university hospital; (2) Methods: A retrospective analysis of the medical records of patients with PDPH has been performed focusing on the techniques of administration, dosing, treatment duration, impact on pain intensity as well as side effects of intranasal lidocaine; (3) Results: During the study period, 5610 obstetric patients received neuraxial anesthesia, of whom 43 (0.77%) developed PDPH. About one third of the patients with PDPH after spinal anesthesia (n = 8), epidural anesthesia (n = 5) or both (n = 2) were treated with intranasal lidocaine. Lidocaine was administered either via gauze compresses (GC, n = 4), a mucosal atomization device (MAD, n = 8) or with a second-line mucosal atomization device due to low gauze compress efficacy (n = 3). All patients treated with lidocaine refused the epidural blood patch. Nebulization of lidocaine resulted in a significant reduction in pain intensity after the first dose (p = 0.008). No relevant side effects developed except sporadic temporal pharyngeal numbness. The utilization of the mucosal atomization device averted the necessity for an epidural blood patch, whether employed as the primary or secondary approach; (4) Conclusions: Our data imply that the mucosal atomization device enhances the efficacy of intranasal lidocaine administration in obstetric patients suffering from PDPH.
DOI:doi:10.3390/biomedicines11123296
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.3390/biomedicines11123296
 Volltext: https://www.mdpi.com/2227-9059/11/12/3296
 kostenfrei: Resolving-System: https://doi.org/10.25673/115202
 DOI: https://doi.org/10.3390/biomedicines11123296
 DOI: https://doi.org/10.25673/115202
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:accidental dural puncture
 epidural anesthesia
 local anesthetics
 midwifery
 pain
 sphenopalatine ganglion
 topical treatment
K10plus-PPN:1881497461
Verknüpfungen:→ Zeitschrift

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