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| Verfasst von: | Najafian Jazi, Maryam [VerfasserIn]  |
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| | Tymorek, Adrian [VerfasserIn] |
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| | Yen, Ting-Yun [VerfasserIn] |
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| | Jose Kavarayil, Felix [VerfasserIn] |
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| | Stingl, Moritz [VerfasserIn] |
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| | Chau, Sherman Richard [VerfasserIn] |
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| | Baskurt, Benay [VerfasserIn] |
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| | García Vilela, Celia [VerfasserIn] |
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| | Allen, Kevin [VerfasserIn] |
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| Titel: | Hippocampal firing fields anchored to a moving object predict homing direction during path-integration-based behavior |
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| Verf.angabe: | Maryam Najafian Jazi, Adrian Tymorek, Ting-Yun Yen, Felix Jose Kavarayil, Moritz Stingl, Sherman Richard Chau, Benay Baskurt, Celia García Vilela & Kevin Allen |
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| E-Jahr: | 2023 |
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| Jahr: | 15 November 2023 |
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| Umfang: | 20 S. |
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| Illustrationen: | Illustrationen |
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| Fussnoten: | Gesehen am 23.02.2024 |
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| Titel Quelle: | Enthalten in: Nature Communications |
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| Ort Quelle: | [London] : Nature Publishing Group UK, 2010 |
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| Jahr Quelle: | 2023 |
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| Band/Heft Quelle: | 14(2023), Artikel-ID 7373, Seite 1-20 |
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| ISSN Quelle: | 2041-1723 |
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| Abstract: | Homing based on path integration (H-PI) is a form of navigation in which an animal uses self-motion cues to keep track of its position and return to a starting point. Despite evidence for a role of the hippocampus in homing behavior, the hippocampal spatial representations associated with H-PI are largely unknown. Here we developed a homing task (AutoPI task) that required a mouse to find a randomly placed lever on an arena before returning to its home base. Recordings from the CA1 area in male mice showed that hippocampal neurons remap between random foraging and AutoPI task, between trials in light and dark conditions, and between search and homing behavior. During the AutoPI task, approximately 25% of the firing fields were anchored to the lever position. The activity of 24% of the cells with a lever-anchored field predicted the homing direction of the animal on each trial. Our results demonstrate that the activity of hippocampal neurons with object-anchored firing fields predicts homing behavior. |
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| DOI: | doi:10.1038/s41467-023-42642-3 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1038/s41467-023-42642-3 |
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| | Volltext: https://www.nature.com/articles/s41467-023-42642-3 |
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| | DOI: https://doi.org/10.1038/s41467-023-42642-3 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Hippocampus |
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| | Spatial memory |
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| K10plus-PPN: | 1881505251 |
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| Verknüpfungen: | → Zeitschrift |
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Hippocampal firing fields anchored to a moving object predict homing direction during path-integration-based behavior / Najafian Jazi, Maryam [VerfasserIn]; 15 November 2023 (Online-Ressource)
