Childhood adversity and emerging psychotic experiences

• Verfasst von: Qiao, Zhiling [VerfasserIn]
• Verfasst von: Lafit, Ginette [VerfasserIn]
• Verfasst von: Lecei, Aleksandra [VerfasserIn]
• Verfasst von: Achterhof, Robin [VerfasserIn]
• Verfasst von: Kirtley, Olivia J [VerfasserIn]
• Verfasst von: Hiekkaranta, Anu P [VerfasserIn]
• Verfasst von: Hagemann, Noëmi [VerfasserIn]
• Verfasst von: Hermans, Karlijn S F M [VerfasserIn]
• Verfasst von: Boets, Bart [VerfasserIn]
• Verfasst von: Reininghaus, Ulrich [VerfasserIn]
• Verfasst von: Myin-Germeys, Inez [VerfasserIn]
• Verfasst von: van Winkel, Ruud [VerfasserIn]
• Titel: Childhood adversity and emerging psychotic experiences
• Titelzusatz: a network perspective
• Verf.angabe: Zhiling Qiao, Ginette Lafit, Aleksandra Lecei, Robin Achterhof, Olivia J. Kirtley, Anu P. Hiekkaranta, Noëmi Hagemann, Karlijn S.F.M. Hermans, Bart Boets, Ulrich Reininghaus, Inez Myin-Germeys, and Ruud van Winkel
• E-Jahr: 2024
• Jahr: January 2024
• Umfang: 12 S.
• Illustrationen: Illustrationen
• Fussnoten: Online veröffentlicht: 15. Juni 2023 ; Gesehen am 26.02.2024
• Titel Quelle: Enthalten in: Schizophrenia bulletin
• Ort Quelle: Oxford : Oxford Univ. Press, 1969
• Jahr Quelle: 2024
• Band/Heft Quelle: 50(2024), Seite 47-58
• ISSN Quelle: 1745-1701
• DOI: doi:10.1093/schbul/sbad079
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 188157945X

Abstract

Childhood adversity is associated with a myriad of psychiatric symptoms, including psychotic experiences (PEs), and with multiple psychological processes that may all mediate these associations.Using a network approach, the present study examined the complex interactions between childhood adversity, PEs, other psychiatric symptoms, and multiple psychological mediators (ie, activity-related and social stress, negative affect, loneliness, threat anticipation, maladaptive cognitive emotion regulation, attachment insecurity) in a general population, adolescent sample (n = 865, age 12-20, 67% female).Centrality analyses revealed a pivotal role of depression, anxiety, negative affect, and loneliness within the network and a bridging role of threat anticipation between childhood adversity and maladaptive cognitive emotion regulation. By constructing shortest path networks, we found multiple existing paths between different categories of childhood adversity and PEs, with symptoms of general psychopathology (ie, anxiety, hostility, and somatization) as the main connective component. Sensitivity analyses confirmed the robustness and stability of the networks. Longitudinal analysis in a subsample with Wave 2 data (n = 161) further found that variables with higher centrality (ie, depression, negative affect, and loneliness) better predicted follow-up PEs.Pathways linking childhood adversity to PEs are complex, with multifaceted psychological and symptom-symptom interactions. They underscore the transdiagnostic, heterotypic nature of mental ill-health in young people experiencing PEs, in agreement with current clinical recommendations.