| |  Online-Ressource |
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| Verfasst von: | Knoedler, Samuel [VerfasserIn]  |
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| | Knödler, Leonard [VerfasserIn] |
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| | Kauke-Navarro, Martin [VerfasserIn] |
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| | Rinkevich, Yuval [VerfasserIn] |
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| | Hundeshagen, Gabriel [VerfasserIn] |
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| | Harhaus-Wähner, Leila [VerfasserIn] |
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| | Kneser, Ulrich [VerfasserIn] |
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| | Pomahac, Bohdan [VerfasserIn] |
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| | Orgill, Dennis P. [VerfasserIn] |
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| | Panayi, Adriana C. [VerfasserIn] |
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| Titel: | Regulatory T cells in skin regeneration and wound healing |
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| Verf.angabe: | Samuel Knoedler, Leonard Knoedler, Martin Kauke-Navarro, Yuval Rinkevich, Gabriel Hundeshagen, Leila Harhaus, Ulrich Kneser, Bohdan Pomahac, Dennis P. Orgill and Adriana C. Panayi |
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| E-Jahr: | 2023 |
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| Jahr: | 23 October 2023 |
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| Umfang: | 23 S. |
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| Illustrationen: | Illustrationen |
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| Fussnoten: | Gesehen am 27.02.2024 |
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| Titel Quelle: | Enthalten in: Military medical research |
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| Ort Quelle: | London : BioMed Central, 2014 |
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| Jahr Quelle: | 2023 |
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| Band/Heft Quelle: | 10(2023), Artikel-ID 49, Seite 1-23 |
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| ISSN Quelle: | 2054-9369 |
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| Abstract: | As the body’s integumentary system, the skin is vulnerable to injuries. The subsequent wound healing processes aim to restore dermal and epidermal integrity and functionality. To this end, multiple tissue-resident cells and recruited immune cells cooperate to efficiently repair the injured tissue. Such temporally- and spatially-coordinated interplay necessitates tight regulation to prevent collateral damage such as overshooting immune responses and excessive inflammation. In this context, regulatory T cells (Tregs) hold a key role in balancing immune homeostasis and mediating cutaneous wound healing. A comprehensive understanding of Tregs’ multifaceted field of activity may help decipher wound pathologies and, ultimately, establish new treatment modalities. Herein, we review the role of Tregs in orchestrating the regeneration of skin adnexa and catalyzing healthy wound repair. Further, we discuss how Tregs operate during fibrosis, keloidosis, and scarring. |
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| DOI: | doi:10.1186/s40779-023-00484-6 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: https://doi.org/10.1186/s40779-023-00484-6 |
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| | kostenfrei: Volltext: https://mmrjournal.biomedcentral.com/articles/10.1186/s40779-023-00484-6 |
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| | DOI: https://doi.org/10.1186/s40779-023-00484-6 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Regulatory T cells (Tregs) |
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| | Skin injury |
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| | Skin regeneration |
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| | Wound healing |
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| | Wound repair |
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| K10plus-PPN: | 1881662861 |
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| Verknüpfungen: | → Zeitschrift |
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Regulatory T cells in skin regeneration and wound healing / Knoedler, Samuel [VerfasserIn]; 23 October 2023 (Online-Ressource)
