| |  Online-Ressource |
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| Verfasst von: | Alencar Fernandes, Felipe Hugo [VerfasserIn]  |
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| | Soares, Sabrina [VerfasserIn] |
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| | Bekbolatova, Elmira [VerfasserIn] |
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| | Boylan, Fábio [VerfasserIn] |
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| | Salgado, Hérida Regina Nunes [VerfasserIn] |
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| Titel: | Pharmacological, toxicological and phytochemical analysis of Spondias dulcis parkinson |
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| Verf.angabe: | Felipe Hugo Alencar Fernandes, Sabrina da Silva Soares, Elmira Bekbolatova, Fábio Boylan, Hérida Regina Nunes Salgado |
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| Jahr: | 2024 |
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| Umfang: | 5 S. |
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| Fussnoten: | Online veröffentlicht: 8. Mai 2023 ; Gesehen am 28.02.2024 |
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| Titel Quelle: | Enthalten in: Natural product research |
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| Ort Quelle: | London [u.a.] : Taylor & Francis, 2003 |
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| Jahr Quelle: | 2024 |
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| Band/Heft Quelle: | 38(2024), 6, Seite 1049-1053 |
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| ISSN Quelle: | 1478-6427 |
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| Abstract: | Spondias dulcis Parkinson have been used in traditional medicine in Asia, Oceania, and South America, for different diseases conditions and as a functional food. The scientific literature described as different potential pharmacology such as antioxidant, anti-inflammatory, antimicrobial, thrombolytic and enzymatic inhibitor. This study aimed to: (1) establish the pharmacological activity in intestinal motility in vivo and antioxidant activity in vitro; (2) perform the acute toxicology test in mouse; (3) characterize the phytochemical profile based on counter-current chromatography (CCC) and NMR analysis. The results revealed a laxative effect of S. dulcis extract and a high antioxidant activity (IC50 = 5.10 for DPPH assay and 14.14 for hydrogen peroxide scavenging test). No side effects were observed in the oral acute toxicity test for a dose up to 2000 mg/kg. The chemical profile was identified by CCC and NMR, and the comparison of the data obtained with previous literature revealed the presence of the flavonoid rutin (Quercetin-3-O-rutinoside) in the extract. |
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| DOI: | doi:10.1080/14786419.2023.2210254 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1080/14786419.2023.2210254 |
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| | Volltext: https://www.tandfonline.com/doi/full/10.1080/14786419.2023.2210254 |
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| | DOI: https://doi.org/10.1080/14786419.2023.2210254 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | antioxidant activity |
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| | countercurrent chromatography |
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| | Laxative activity |
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| | rutin |
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| K10plus-PPN: | 1882042646 |
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| Verknüpfungen: | → Zeitschrift |
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Pharmacological, toxicological and phytochemical analysis of Spondias dulcis parkinson / Alencar Fernandes, Felipe Hugo [VerfasserIn]; 2024 (Online-Ressource)
