| Online-Ressource |
Verfasst von: | Steen, Henning [VerfasserIn]  |
| Montenbruck, Moritz [VerfasserIn]  |
| Kallifatidis, Alexandros [VerfasserIn]  |
| André, Florian [VerfasserIn]  |
| Frey, Norbert [VerfasserIn]  |
| Kelle, Sebastian [VerfasserIn]  |
| Korosoglou, Grigorios [VerfasserIn]  |
Titel: | Multi-parametric non-contrast cardiac magnetic resonance for the differentiation between cardiac amyloidosis and hypertrophic cardiomyopathy |
Verf.angabe: | Henning Steen, Moritz Montenbruck, Alexandros Kallifatidis, Florian Andre, Norbert Frey, Sebastian Kelle & Grigorios Korosoglou |
E-Jahr: | 2023 |
Jahr: | 14 December 2023 |
Umfang: | 12 S. |
Illustrationen: | Illustrationen |
Fussnoten: | Gesehen am 07.03.2024 ; Online veröffentlicht: 14. Dezember 2023 |
Titel Quelle: | Enthalten in: Clinical research in cardiology |
Ort Quelle: | Berlin : Springer, 2006 |
Jahr Quelle: | 2023 |
Band/Heft Quelle: | 113(2023), Seite 469-480 |
ISSN Quelle: | 1861-0692 |
Abstract: | Aim To evaluate the ability of fast strain-encoded (SENC) cardiac magnetic resonance (CMR) derived myocardial strain and native T1 mapping to discriminate between hypertrophic cardiomyopathy (HCM) and cardiac amyloidosis.Methods Ninety nine patients (57 with hypertrophic cardiomyopathy and 42 with cardiac amyloidosis) were systematically analysed. LV-ejection fraction, LV-mass index, septal wall thickness and native T1 mapping values were assessed. In addition, global circumferential and longitudinal strain and segmental circumferential and longitudinal strain in basal, mid-ventricular, and apical segments were calculated. A ratio was built by dividing native T1 values by basal segmental strain (T1-to-basal segmental strain ratio).Results Myocardial strain was equally distributed in apical and basal segments in HCM patients, whereas an apical sparing with less impaired apical strain was noticed in cardiac amyloidosis (apical-to-basal-ratio of 1.01 +/- 0.23 versus 1.20 +/- 0.28, p < 0.001). T1 values were significantly higher in amyloidosis compared to HCM patients (1170.7 +/- 66.4 ms versus 1078.3 +/- 57.4ms, p < 0.001). The T1-to-basal segmental strain ratio exhibited high accuracy for the differentiation between the two clinical entities (Sensitivity = 85%, Specificity = 77%, AUC = 0.90, 95% CI = 0.81-0.95, p < 0.001). Multivariable analysis showed that age and the T1-to-basal-strain-ratio were the most robust factors for the differentiation between HCM and cardiac amyloidosis.Conclusion The T1-to-basal-segmental strain ratio, combining information from segmental circumferential and longitudinal strain and native T1 mapping aids the differentiation between HCM and cardiac amyloidosis with high accuracy and within a fast CMR protocol, obviating the need for contrast agent administration. |
DOI: | doi:10.1007/s00392-023-02348-4 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1007/s00392-023-02348-4 |
| Volltext: https://link.springer.com/article/10.1007/s00392-023-02348-4 |
| DOI: https://doi.org/10.1007/s00392-023-02348-4 |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | ASSOCIATION |
| Cardiac amyloidosis |
| CONSENSUS |
| DIAGNOSTIC CLASSIFICATION |
| FAILURE |
| Fast strain-Encoded CMR (fast-SENC) |
| HEART |
| Hypertrophic cardiomyopathy |
| LATE GADOLINIUM ENHANCEMENT |
| LONGITUDINAL STRAIN |
| Myocardial hypertrophy |
| MYOCARDIAL STRAIN |
| Non-contrast |
| T1 |
| T1 mapping |
| TISSUE |
K10plus-PPN: | 1882872371 |
Verknüpfungen: | → Zeitschrift |
Multi-parametric non-contrast cardiac magnetic resonance for the differentiation between cardiac amyloidosis and hypertrophic cardiomyopathy / Steen, Henning [VerfasserIn]; 14 December 2023 (Online-Ressource)