| |  Online-Ressource |
|---|
| Verfasst von: | Vlaški, Tomislav [VerfasserIn]  |
|---|
| | Slavic, Marija [VerfasserIn] |
|---|
| | Caspari, Reiner [VerfasserIn] |
|---|
| | Bilsing, Bettine [VerfasserIn] |
|---|
| | Fischer, Harald [VerfasserIn] |
|---|
| | Brenner, Hermann [VerfasserIn] |
|---|
| | Schöttker, Ben [VerfasserIn] |
|---|
| Titel: | From a clustering of adverse symptoms after colorectal cancer therapy to chronic fatigue and low ability to work |
|---|
| Titelzusatz: | a cohort study analysis with 3 months of follow-up |
|---|
| Verf.angabe: | Tomislav Vlaski, Marija Slavic, Reiner Caspari, Bettine Bilsing, Harald Fischer, Hermann Brenner and Ben Schöttker |
|---|
| E-Jahr: | 2024 |
|---|
| Jahr: | 1 January 2024 |
|---|
| Umfang: | 17 S. |
|---|
| Illustrationen: | Illustrationen |
|---|
| Fussnoten: | Gesehen am 02.04.2024 |
|---|
| Titel Quelle: | Enthalten in: Cancers |
|---|
| Ort Quelle: | Basel : MDPI, 2009 |
|---|
| Jahr Quelle: | 2024 |
|---|
| Band/Heft Quelle: | 16(2024), 1, Artikel-ID 202, Seite 1-17 |
|---|
| ISSN Quelle: | 2072-6694 |
|---|
| Abstract: | In colorectal cancer (CRC) patients, apart from fatigue, psychological and physical symptoms often converge, affecting their quality of life and ability to work. Our objective was to ascertain symptom clusters within a year following CRC treatment and their longitudinal association with persistent fatigue and reduced work ability at the 3-month follow-up. We used data from MIRANDA, a multicenter cohort study enrolling adult CRC patients who are starting a 3-week in-patient rehabilitation within a year post-curative CRC treatment. Participants completed questionnaires evaluating symptoms at the start of rehabilitation (baseline) and after three months. We performed an exploratory factor analysis to analyze the clustering of symptoms at baseline. Longitudinal analysis was performed using a multivariable linear regression model with dichotomized symptoms at baseline as independent variables, and the change in fatigue and ability to work from baseline to 3-month-follow-up as separate outcomes, adjusted for covariates. We identified six symptom clusters: fatigue, gastrointestinal symptoms, pain, psychosocial symptoms, urinary symptoms, and chemotherapy side effects. At least one symptom from each factor was associated with higher fatigue or reduced ability to work at the 3-month follow-up. This study highlights the interplay of multiple symptoms in influencing fatigue and work ability among CRC patients post-rehabilitation. |
|---|
| DOI: | doi:10.3390/cancers16010202 |
|---|
| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: https://doi.org/10.3390/cancers16010202 |
|---|
| | kostenfrei: Volltext: https://www.mdpi.com/2072-6694/16/1/202 |
|---|
| | DOI: https://doi.org/10.3390/cancers16010202 |
|---|
| Datenträger: | Online-Ressource |
|---|
| Sprache: | eng |
|---|
| Sach-SW: | ability to work |
|---|
| | colorectal cancer |
|---|
| | fatigue |
|---|
| | rehabilitation |
|---|
| | symptom clusters |
|---|
| K10plus-PPN: | 1884701922 |
|---|
| Verknüpfungen: | → Zeitschrift |
|---|
From a clustering of adverse symptoms after colorectal cancer therapy to chronic fatigue and low ability to work / Vlaški, Tomislav [VerfasserIn]; 1 January 2024 (Online-Ressource)
