| Online-Ressource |
Verfasst von: | Kühl, Rea [VerfasserIn]  |
| Feyer, Jule [VerfasserIn]  |
| Limbach, Matthias [VerfasserIn]  |
| Pahl, Antonia [VerfasserIn]  |
| Stoelzel, Friederike [VerfasserIn]  |
| Beck, Heidrun [VerfasserIn]  |
| Wegner, Annika [VerfasserIn]  |
| Rosenberger, Friederike [VerfasserIn]  |
| Dreger, Peter [VerfasserIn]  |
| Luft, Thomas [VerfasserIn]  |
| Wiskemann, Joachim [VerfasserIn]  |
Titel: | Prehabilitative high-intensity interval training and resistance exercise in patients prior allogeneic stem cell transplantation |
Verf.angabe: | Rea Kuehl, Jule Feyer, Matthias Limbach, Antonia Pahl, Friederike Stoelzel, Heidrun Beck, Annika Wegner, Friederike Rosenberger, Peter Dreger, Thomas Luft & Joachim Wiskemann |
E-Jahr: | 2023 |
Jahr: | 12 December 2023 |
Umfang: | 10 S. |
Illustrationen: | Illustrationen |
Fussnoten: | Gesehen am 04.04.2024 |
Titel Quelle: | Enthalten in: Scientific reports |
Ort Quelle: | [London] : Springer Nature, 2011 |
Jahr Quelle: | 2023 |
Band/Heft Quelle: | 13(2023), Artikel-ID 22069, Seite 1-10 |
ISSN Quelle: | 2045-2322 |
Abstract: | Physical capacity prior allogeneic stem cell transplantation (allo-HCT) has been shown as a relevant prognostic factor for survival after transplant. Therefore, we evaluated feasibility and preliminary efficacy of a high-intensity interval training (HIIT) and moderate to high-intensity resistance exercise (RE) to increase physical capacity in patient’s prior allo-HCT. In this multicentre single arm pilot study, a supervised exercise program was performed twice weekly for 4-12 weeks prior allo-HCT, depending on the individual time remaining. Outcomes were feasibility (recruitment, adherence, safety), physical capacity (cardiorespiratory fitness [VO2peak], muscle strength) and patient reported outcomes (physical functioning, fatigue). Thirty patients were intended, 16 could be included, and 14 completed post intervention assessment (75% male, 55 ± 11 years). The study was stopped early due to a low recruitment rate. Nine patients (64%) reached the initial minimum planned number of eight exercise sessions. Individual adherence was high with 92% for HIIT and 85% for RE. 87% of all performed exercise sessions were completed without complaints and VO2peak increased significantly from 20.4 to 23.4 ml/kg/min. The low recruitment rate suggests that initiation of the intervention concept immediately before allo-HCT is feasible only in a small number of patients. In particular, the timeframe directly prior allo-HCT seems too short for exercise interventions, although the exercise program was designed to improve outcomes in a very short time frame. HIIT and RE were feasible, effective and well accepted by the included patients. |
DOI: | doi:10.1038/s41598-023-49420-7 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: https://doi.org/10.1038/s41598-023-49420-7 |
| kostenfrei: Volltext: https://www.nature.com/articles/s41598-023-49420-7 |
| DOI: https://doi.org/10.1038/s41598-023-49420-7 |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | Cancer |
| Haematological cancer |
| Oncology |
K10plus-PPN: | 1885028628 |
Verknüpfungen: | → Zeitschrift |
Prehabilitative high-intensity interval training and resistance exercise in patients prior allogeneic stem cell transplantation / Kühl, Rea [VerfasserIn]; 12 December 2023 (Online-Ressource)