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Status: Bibliographieeintrag

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Verfasst von:Kühl, Rea [VerfasserIn]   i
 Feyer, Jule [VerfasserIn]   i
 Limbach, Matthias [VerfasserIn]   i
 Pahl, Antonia [VerfasserIn]   i
 Stoelzel, Friederike [VerfasserIn]   i
 Beck, Heidrun [VerfasserIn]   i
 Wegner, Annika [VerfasserIn]   i
 Rosenberger, Friederike [VerfasserIn]   i
 Dreger, Peter [VerfasserIn]   i
 Luft, Thomas [VerfasserIn]   i
 Wiskemann, Joachim [VerfasserIn]   i
Titel:Prehabilitative high-intensity interval training and resistance exercise in patients prior allogeneic stem cell transplantation
Verf.angabe:Rea Kuehl, Jule Feyer, Matthias Limbach, Antonia Pahl, Friederike Stoelzel, Heidrun Beck, Annika Wegner, Friederike Rosenberger, Peter Dreger, Thomas Luft & Joachim Wiskemann
E-Jahr:2023
Jahr:12 December 2023
Umfang:10 S.
Illustrationen:Illustrationen
Fussnoten:Gesehen am 04.04.2024
Titel Quelle:Enthalten in: Scientific reports
Ort Quelle:[London] : Springer Nature, 2011
Jahr Quelle:2023
Band/Heft Quelle:13(2023), Artikel-ID 22069, Seite 1-10
ISSN Quelle:2045-2322
Abstract:Physical capacity prior allogeneic stem cell transplantation (allo-HCT) has been shown as a relevant prognostic factor for survival after transplant. Therefore, we evaluated feasibility and preliminary efficacy of a high-intensity interval training (HIIT) and moderate to high-intensity resistance exercise (RE) to increase physical capacity in patient’s prior allo-HCT. In this multicentre single arm pilot study, a supervised exercise program was performed twice weekly for 4-12 weeks prior allo-HCT, depending on the individual time remaining. Outcomes were feasibility (recruitment, adherence, safety), physical capacity (cardiorespiratory fitness [VO2peak], muscle strength) and patient reported outcomes (physical functioning, fatigue). Thirty patients were intended, 16 could be included, and 14 completed post intervention assessment (75% male, 55 ± 11 years). The study was stopped early due to a low recruitment rate. Nine patients (64%) reached the initial minimum planned number of eight exercise sessions. Individual adherence was high with 92% for HIIT and 85% for RE. 87% of all performed exercise sessions were completed without complaints and VO2peak increased significantly from 20.4 to 23.4 ml/kg/min. The low recruitment rate suggests that initiation of the intervention concept immediately before allo-HCT is feasible only in a small number of patients. In particular, the timeframe directly prior allo-HCT seems too short for exercise interventions, although the exercise program was designed to improve outcomes in a very short time frame. HIIT and RE were feasible, effective and well accepted by the included patients.
DOI:doi:10.1038/s41598-023-49420-7
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

kostenfrei: Volltext: https://doi.org/10.1038/s41598-023-49420-7
 kostenfrei: Volltext: https://www.nature.com/articles/s41598-023-49420-7
 DOI: https://doi.org/10.1038/s41598-023-49420-7
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:Cancer
 Haematological cancer
 Oncology
K10plus-PPN:1885028628
Verknüpfungen:→ Zeitschrift

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