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Verfasst von:El-Battrawy, Ibrahim [VerfasserIn]   i
 Erath, Julia W. [VerfasserIn]   i
 Vamos, Mate [VerfasserIn]   i
 Aweimer, Assem [VerfasserIn]   i
 Mügge, Andreas [VerfasserIn]   i
 Lang, Siegfried [VerfasserIn]   i
 Ansari, Uzair [VerfasserIn]   i
 Gietzen, Thorsten [VerfasserIn]   i
 Akın, Ibrahim [VerfasserIn]   i
Titel:A case series of concomitant cardiac electrical disease among Takotsubo Syndrome patients and literature review
Verf.angabe:Ibrahim El-Battrawy, Julia W. Erath, Mate Vamos, Assem Aweimer, Andreas Mügge, Siegfried Lang, Uzair Ansari, Thorsten Gietzen and Ibrahim Akin
E-Jahr:2022
Jahr:9 March 2022
Umfang:9 S.
Illustrationen:Illustrationen
Fussnoten:Gesehen am 16.04.2024
Weitere Titel:Titel des übergeordneten Special issue: Takotsubo Syndrome, Short QT Syndrome and Brugada Syndrome
Titel Quelle:Enthalten in: Journal of cardiovascular development and disease
Ort Quelle:Basel : MDPI AG, 2014
Jahr Quelle:2022
Band/Heft Quelle:9(2022), 3, Artikel-ID 79, Seite 1-9
ISSN Quelle:2308-3425
Abstract:The pathophysiology of Takotsubo Syndrome (TTS) is not completely understood and the trigger of sudden cardiac death (SCD) in TTS is not clear either. We therefore sought to find an association between TTS and primary electrical diseases. A total of 148 TTS patients were analyzed between 2003 and 2017 in a bi-centric manner. Additionally, a literature review was performed. The patients were included in an ongoing retrospective cohort database. The coexistence of TTS and primary electrical diseases was confirmed in five cases as the following: catecholaminergic polymorphic ventricular tachycardia (CPVT, 18-year-old female) (n = 1), LQTS 1 (72-year-old female and 65-year-old female) (n = 2), LQTS 2 (17-year-old female) (n = 1), and LQTS in the absence of mutations (22-year-old female). Four patients suffered from malignant tachyarrhythmia and recurrent syncope after TTS. Except for the CPVT patient and one LQTS 1 patient, all other cases underwent subcutaneous ICD implantation. An event recorder of the CPVT patient after starting beta-blocker did not detect arrhythmias. The diagnosis of primary electrical disease was in 80% of cases unmasked on a TTS event. This diagnosis triggered a family clinical and genetic screening confirming the diagnosis of primary electrical disease. A subsequent literature review identified five cases as the following: a congenital atrioventricular block (n = 1), a Jervell and Lange-Nielsen Syndrome (n = 1), and a family LQTS in the absence of a mutation (n = 2), LQTS 2 (n = 1). A primary electrical disease should be suspected in young and old TTS patients with a family history of sudden cardiac death. In suspected cases, e.g., ongoing QT interval prolongation, despite recovery of left ventricular ejection fraction a family screening is recommended.
DOI:doi:10.3390/jcdd9030079
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

kostenfrei: Volltext: https://doi.org/10.3390/jcdd9030079
 kostenfrei: Volltext: https://www.mdpi.com/2308-3425/9/3/79
 DOI: https://doi.org/10.3390/jcdd9030079
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:acquired LQT syndrome
 beta-blocker
 catecholamine excess
 estrogen
 mortality
 Takotsubo Syndrome
K10plus-PPN:1885922558
Verknüpfungen:→ Zeitschrift

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