Navigation überspringen
Universitätsbibliothek Heidelberg
Status: Bibliographieeintrag

Verfügbarkeit
Standort: ---
Exemplare: ---
heiBIB
 Online-Ressource
Verfasst von:Bommer, Jürgen [VerfasserIn]   i
 Becker, Klaus-Peter [VerfasserIn]   i
 Urbaschek, Renate [VerfasserIn]   i
Titel:Potential transfer of endotoxin across high-flux polysulfone membranes.
Verf.angabe:J. Bommer, K.P. Becker, R. Urbaschek
E-Jahr:1996
Jahr:June 1996
Umfang:6 S.
Fussnoten:Gesehen am 08.05.2024
Titel Quelle:Enthalten in: American Society of NephrologyJournal of the American Society of Nephrology
Ort Quelle:Washington, DC : American Society of Nephrology, 1990
Jahr Quelle:1996
Band/Heft Quelle:7(1996), 6, Seite 883-888
ISSN Quelle:1533-3450
Abstract:It has been postulated that synthetic membranes, such as polysulfone membranes, are rather impermeable for endotoxin or endotoxin fragments and can be used for sterile filtration of dialysate. It has never been investigated, however, whether endotoxin permeability may be different in commercially available polysulfone membranes. In vitro, we found a significantly different permeability for endotoxin in two standard dialyzers and one test dialyzer with high-flux polysulfone membranes. In contrast to the F-60 dialyzer with a very low permeability for endotoxin, a stepwise increasing load of endotoxin concentration in the dialysate compartment of the PN 1913 test dialyzer and Primus 1350 polysulfone dialyzer was followed by a stepwise increase of endotoxin in the blood compartment. A significant transfer across the membranes was found when the endotoxin concentration in the dialysate compartment was > 10 ng/mL in the PN 1913 and > 0.5 ng/mL in the Primus 1350. In the latter, about 0.5% of the endotoxin concentration of the dialysate compartment was found in the blood compartment. The data suggest that manufacturers have to evaluate the performance and other properties of their synthetic membranes in detail.
DOI:doi:10.1681/ASN.V76883
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1681/ASN.V76883
 Volltext: https://journals.lww.com/jasn/abstract/1996/06000/potential_transfer_of_endotoxin_across_high_flux.10.aspx
 DOI: https://doi.org/10.1681/ASN.V76883
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1888126930
Verknüpfungen:→ Zeitschrift

Permanenter Link auf diesen Titel (bookmarkfähig):  https://katalog.ub.uni-heidelberg.de/titel/69212305   QR-Code
zum Seitenanfang