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| Verfasst von: | Maurus, Isabel [VerfasserIn]  |
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| | Röll, Lukas [VerfasserIn] |
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| | Lembeck, Moritz [VerfasserIn] |
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| | Papazova, Irina [VerfasserIn] |
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| | Greska, David [VerfasserIn] |
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| | Muenz, Susanne [VerfasserIn] |
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| | Wagner, Elias Maximilian [VerfasserIn] |
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| | Campana, Mattia [VerfasserIn] |
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| | Schwaiger, Rebecca [VerfasserIn] |
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| | Schneider-Axmann, Thomas [VerfasserIn] |
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| | Rosenberger, Kerstin [VerfasserIn] |
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| | Hellmich, Martin [VerfasserIn] |
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| | Sykorova, Eliska [VerfasserIn] |
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| | Thieme, Cristina E. [VerfasserIn] |
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| | Vogel, Bob [VerfasserIn] |
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| | Harder, Carolin [VerfasserIn] |
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| | Mohnke, Sebastian [VerfasserIn] |
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| | Huppertz, Charlotte [VerfasserIn] |
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| | Roeh, Astrid [VerfasserIn] |
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| | Keller-Varady, Katriona [VerfasserIn] |
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| | Malchow, Berend [VerfasserIn] |
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| | Walter, Henrik [VerfasserIn] |
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| | Wolfarth, Bernd [VerfasserIn] |
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| | Wolwer, Wolfgang [VerfasserIn] |
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| | Henkel, Karsten [VerfasserIn] |
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| | Hirjak, Dusan [VerfasserIn] |
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| | Schmitt, Andrea [VerfasserIn] |
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| | Hasan, Alkomiet [VerfasserIn] |
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| | Meyer-Lindenberg, Andreas [VerfasserIn] |
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| | Falkai, Peter [VerfasserIn] |
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| Titel: | Exercise as an add-on treatment in individuals with schizophrenia |
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| Titelzusatz: | results from a large multicenter randomized controlled trial |
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| Verf.angabe: | Isabel Maurus, Lukas Roell, Moritz Lembeck, Irina Papazova, David Greska, Susanne Muenz, Elias Wagner, Mattia Campana, Rebecca Schwaiger, Thomas Schneider-Axmann, Kerstin Rosenberger, Martin Hellmich, Eliska Sykorova, Cristina E. Thieme, Bob O. Vogel, Carolin Harder, Sebastian Mohnke, Charlotte Huppertz, Astrid Roeh, Katriona Keller-Varady, Berend Malchow, Henrik Walter, Bernd Wolfarth, Wolfgang Wolwer, Karsten Henkel, Dusan Hirjak, Andrea Schmitt, Alkomiet Hasan, Andreas Meyer-Lindenberg, Peter Falkai |
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| E-Jahr: | 2023 |
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| Jahr: | 10 September 2023 |
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| Umfang: | 11 S. |
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| Illustrationen: | Illustrationen |
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| Fussnoten: | Gesehen am 16.05.2024 |
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| Titel Quelle: | Enthalten in: Psychiatry research |
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| Ort Quelle: | Amsterdam [u.a.] : Elsevier Science, 1979 |
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| Jahr Quelle: | 2023 |
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| Band/Heft Quelle: | 328(2023), Artikel-ID 115480, Seite 1-11 |
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| ISSN Quelle: | 1872-7123 |
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| Abstract: | Current treatment methods do not achieve recovery for most individuals with schizophrenia, and symptoms such as negative symptoms and cognitive deficits often persist. Aerobic endurance training has been suggested as a potential add-on treatment targeting both physical and mental health. We performed a large-scale multicenter, rater-blind, parallel-group randomized controlled clinical trial in individuals with stable schizophrenia. Participants underwent a professionally supervised six-month training comprising either aerobic endurance training (AET) or flexibility, strengthening, and balance training (FSBT, control group), follow-up was another six months. The primary endpoint was all-cause discontinuation (ACD); secondary endpoints included effects on psychopathology, cognition, functioning, and cardiovascular risk. In total, 180 participants were randomized. AET was not superior to FSBT in ACD and most secondary outcomes, with dropout rates of 59.55% and 57.14% in the six-month active phase, respectively. However, both groups showed significant improvements in positive, general, and total symptoms, levels of functioning and in cognitive performance. A higher training frequency additionally promoted further memory domains. Participants with higher baseline cognitive abilities were more likely to respond to the interventions. Our results support integrating exercise into schizophrenia treatment, while future studies should aim to develop personalized training recommendations to maximize exercise-induced benefits. |
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| DOI: | doi:10.1016/j.psychres.2023.115480 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1016/j.psychres.2023.115480 |
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| | Volltext: https://www.sciencedirect.com/science/article/pii/S0165178123004304?via%3Dihub |
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| | DOI: https://doi.org/10.1016/j.psychres.2023.115480 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Cardiovascular risk |
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| | Clinical trial |
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| | COGNITION |
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| | HEALTH |
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| | INTERVENTIONS |
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| | Lifestyle intervention |
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| | METAANALYSIS |
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| | NEGATIVE SYMPTOMS |
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| | Physical activity |
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| | Psychosis |
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| | RECOVERY |
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| | SCALE |
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| | TREATMENT OUTCOMES |
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| K10plus-PPN: | 1888949775 |
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| Verknüpfungen: | → Zeitschrift |
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Exercise as an add-on treatment in individuals with schizophrenia / Maurus, Isabel [VerfasserIn]; 10 September 2023 (Online-Ressource)
