| |  Online-Ressource |
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| Verfasst von: | Schwegler, Niklas [VerfasserIn]  |
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| | Gebert, Tanisha [VerfasserIn] |
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| | Villiou, Maria [VerfasserIn] |
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| | Colombo, Federico [VerfasserIn] |
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| | Schamberger, Barbara [VerfasserIn] |
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| | Selhuber-Unkel, Christine [VerfasserIn] |
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| | Thomas, Franziska [VerfasserIn] |
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| | Blasco, Eva [VerfasserIn] |
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| Titel: | Multimaterial 3D laser printing of cell-adhesive and cell-repellent hydrogels |
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| Verf.angabe: | Niklas Schwegler, Tanisha Gebert, Maria Villiou, Federico Colombo, Barbara Schamberger, Christine Selhuber-Unkel, Franziska Thomas, and Eva Blasco |
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| E-Jahr: | 2024 |
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| Jahr: | 06 May 2024 |
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| Umfang: | 9 S. |
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| Fussnoten: | Gesehen am 23.05.2024 |
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| Titel Quelle: | Enthalten in: Small |
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| Ort Quelle: | Weinheim : Wiley-VCH, 2005 |
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| Jahr Quelle: | 2024 |
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| Band/Heft Quelle: | (2024), early view, Artikel-Nummer 2401344, Seite 1-9 |
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| ISSN Quelle: | 1613-6829 |
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| Abstract: | Here, a straightforward method is reported for manufacturing 3D microstructured cell-adhesive and cell-repellent multimaterials using two-photon laser printing. Compared to existing strategies, this approach offers bottom-up molecular control, high customizability, and rapid and precise 3D fabrication. The printable cell-adhesive polyethylene glycol (PEG) based material includes an Arg-Gly-Asp (RGD) containing peptide synthesized through solid-phase peptide synthesis, allowing for precise control of the peptide design. Remarkably, minimal amounts of RGD peptide (< 0.1 wt%) suffice for imparting cell-adhesiveness, while maintaining identical mechanical properties in the 3D printed microstructures to those of the cell-repellent, PEG-based material. Fluorescent labeling of the RGD peptide facilitates visualization of its presence in cell-adhesive areas. To demonstrate the broad applicability of the system, the fabrication of cell-adhesive 2.5D and 3D structures is shown, fostering the adhesion of fibroblast cells within these architectures. Thus, this approach allows for the printing of high-resolution, true 3D structures suitable for diverse applications, including cellular studies in complex environments. |
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| DOI: | doi:10.1002/smll.202401344 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1002/smll.202401344 |
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| | Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/smll.202401344 |
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| | DOI: https://doi.org/10.1002/smll.202401344 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | cell adhesion |
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| | direct laser writing |
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| | hydrogels |
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| | RGD |
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| | two-photon |
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| K10plus-PPN: | 1889663778 |
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| Verknüpfungen: | → Zeitschrift |
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Multimaterial 3D laser printing of cell-adhesive and cell-repellent hydrogels / Schwegler, Niklas [VerfasserIn]; 06 May 2024 (Online-Ressource)
