| Online-Ressource |
Verfasst von: | Gauter-Fleckenstein, Benjamin [VerfasserIn]  |
| Nguyen, Julia [VerfasserIn]  |
| Jahnke, Lennart [VerfasserIn]  |
| Gaiser, Timo [VerfasserIn]  |
| Rudic, Boris [VerfasserIn]  |
| Büttner, Sylvia [VerfasserIn]  |
| Wenz, Frederik [VerfasserIn]  |
| Borggrefe, Martin [VerfasserIn]  |
| Tueluemen, Erol [VerfasserIn]  |
Titel: | Interaction between CIEDs and modern radiotherapy techniques |
Titelzusatz: | flattening filter free-VMAT, dose-rate effects, scatter radiation, and neutron-generating energies |
Verf.angabe: | Benjamin Gauter-Fleckenstein, Julia Nguyen, Lennart Jahnke, Timo Gaiser, Boris Rudic, Sylvia Büttner, Frederik Wenz, Martin Borggrefe, Erol Tülümen |
E-Jahr: | 2020 |
Jahr: | November 2020 |
Umfang: | 7 S. |
Fussnoten: | Gesehen am 31.05.2023 |
Titel Quelle: | Enthalten in: Radiotherapy and oncology |
Ort Quelle: | Amsterdam [u.a.] : Elsevier Science, 1983 |
Jahr Quelle: | 2020 |
Band/Heft Quelle: | 152(2020) vom: Nov., Seite 196-202 |
ISSN Quelle: | 1879-0887 |
Abstract: | Background and purpose - Providing evidence for radiotherapy (RT)-induced effects on cardiac implantable electric devices (CIEDs) with focus on flattening filter free-volumetric modulated arc therapy (FFF-VMAT) at 6 and 10 MV as well as 3D-conformal radiotherapy (3D-CRT) at 18 MV. - Materials and methods - 68 CIEDs (64 implantable cardioverter-defibrillators (ICDs) and 4 cardiac pacemakers (PMs)) were located on the left chest position on a slab phantom and irradiated under telemetrical surveillance either directly, or distant to 3D-CRT or FFF-VMAT, dose-rate 2500 cGy/min, and target dose of 150 Gy. Devices were placed within, close by (2.5 cm and 5 cm), and distant (35 cm) to the radiation field. Scatter radiation (SR) and photon neutrons (PN) were recorded. CIEDs were investigated in following groups: 1a) 18 MV 3D-CRT − 4 ICDs/4 PMs out of radiation field, 1b) 18 MV open field − 4 ICDs/4 PMs within radiation field, 2) 6 MV FFF-VMAT, 15 ICDs in 35 cm distance to VMAT, 3) 10 MV-FFF VMAT, 15 ICDs in 35 cm distance to VMAT, 4) 6 MV FFF-VMAT, 15 ICDs in 2.5 cm distance to VMAT, 5) 10 MV FFF-VMAT, 15 ICDs in 2.5 cm distance to VMAT. - Results - No incidents occurred at 6 MV FFF. 10 MV FFF-VMAT and 18 MV 3D-CRT resulted in data loss, reset, and erroneous sensing with inhibition of pacing (leading to inadequate defibrillation) in 8/34 ICDs and 2/4 PMs which were not located within radiation. Direct radiation triggered instantaneous defibrillation in 3/4 ICDs. - Conclusions - 6 MV FFF-VMAT is safe even at high dose-rates of 2500 cGy/min, regardless whether CIEDs are located close (2.5 cm) or distant (35 cm) to the radiation beam. CIEDs should never be placed within radiation and energy should always be limited to 6 MV. At 6 MV, VMAT at high dose-rates can be used to treat tumors, which are located close to CIEDs. |
DOI: | doi:10.1016/j.radonc.2019.12.007 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1016/j.radonc.2019.12.007 |
| Volltext: https://www.sciencedirect.com/science/article/pii/S0167814019335078 |
| DOI: https://doi.org/10.1016/j.radonc.2019.12.007 |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | Cardiac pacemaker |
| Dose-rate effects |
| Flattening filter free-VMAT |
| Implantable cardioverter-defibrillator |
| Neutron-generating energies |
| Scatter radiation |
K10plus-PPN: | 1890393711 |
Verknüpfungen: | → Zeitschrift |
Interaction between CIEDs and modern radiotherapy techniques / Gauter-Fleckenstein, Benjamin [VerfasserIn]; November 2020 (Online-Ressource)