| |  Online-Ressource |
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| Verfasst von: | Melzig, Claudius [VerfasserIn]  |
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| | Hartmann, Sibylle [VerfasserIn] |
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| | Steuwe, Andrea [VerfasserIn] |
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| | Egger, Jan [VerfasserIn] |
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| | Do, Thuy [VerfasserIn] |
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| | Geisbüsch, Philipp [VerfasserIn] |
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| | Kauczor, Hans-Ulrich [VerfasserIn] |
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| | Rengier, Fabian [VerfasserIn] |
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| | Fink, Matthias A. [VerfasserIn] |
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| Titel: | BMI-adapted double low-dose dual-source aortic CT for endoleak detection after endovascular repair |
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| Titelzusatz: | a prospective intra-individual diagnostic accuracy study |
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| Verf.angabe: | Claudius Melzig, Sibylle Hartmann, Andrea Steuwe, Jan Egger, Thuy D. Do, Philipp Geisbüsch, Hans-Ulrich Kauczor, Fabian Rengier and Matthias A. Fink |
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| E-Jahr: | 2024 |
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| Jahr: | 27 January 2024 |
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| Umfang: | 12 S. |
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| Fussnoten: | Ilustrationen ; Gesehen am 10.06.2024 |
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| Titel Quelle: | Enthalten in: Diagnostics |
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| Ort Quelle: | Basel : MDPI, 2011 |
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| Jahr Quelle: | 2024 |
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| Band/Heft Quelle: | 14(2024), 3, Artikel-ID 280, Seite 1-12 |
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| ISSN Quelle: | 2075-4418 |
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| Abstract: | Purpose: To assess the diagnostic accuracy of BMI-adapted, low-radiation and low-iodine dose, dual-source aortic CT for endoleak detection in non-obese and obese patients following endovascular aortic repair. Methods: In this prospective single-center study, patients referred for follow-up CT after endovascular repair with a history of at least one standard triphasic (native, arterial and delayed phase) routine CT protocol were enrolled. Patients were divided into two groups and allocated to a BMI-adapted (group A, BMI < 30 kg/m2; group B, BMI ≥ 30 kg/m2) double low-dose CT (DLCT) protocol comprising single-energy arterial and dual-energy delayed phase series with virtual non-contrast (VNC) reconstructions. An in-patient comparison of the DLCT and routine CT protocol as reference standard was performed regarding differences in diagnostic accuracy, radiation dose, and image quality. Results: Seventy-five patients were included in the study (mean age 73 ± 8 years, 63 (84%) male). Endoleaks were diagnosed in 20 (26.7%) patients, 11 of 53 (20.8%) in group A and 9 of 22 (40.9%) in group B. Two radiologists achieved an overall diagnostic accuracy of 98.7% and 97.3% for endoleak detection, with 100% in group A and 95.5% and 90.9% in group B. All examinations were diagnostic. The DLCT protocol reduced the effective dose from 10.0 ± 3.6 mSv to 6.1 ± 1.5 mSv (p < 0.001) and the total iodine dose from 31.5 g to 14.5 g in group A and to 17.4 g in group B. Conclusion: Optimized double low-dose dual-source aortic CT with VNC, arterial and delayed phase images demonstrated high diagnostic accuracy for endoleak detection and significant radiation and iodine dose reductions in both obese and non-obese patients compared to the reference standard of triple phase, standard radiation and iodine dose aortic CT. |
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| DOI: | doi:10.3390/diagnostics14030280 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: https://doi.org/10.3390/diagnostics14030280 |
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| | kostenfrei: Volltext: https://www.mdpi.com/2075-4418/14/3/280 |
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| | DOI: https://doi.org/10.3390/diagnostics14030280 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | endoleak imaging |
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| | EVAR surveillance |
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| | low-dose CT |
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| | quantitative analysis |
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| K10plus-PPN: | 1890966215 |
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| Verknüpfungen: | → Zeitschrift |
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BMI-adapted double low-dose dual-source aortic CT for endoleak detection after endovascular repair / Melzig, Claudius [VerfasserIn]; 27 January 2024 (Online-Ressource)
