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| Verfasst von: | You, Ya-Ting [VerfasserIn]  |
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| | Zuo, Hao [VerfasserIn] |
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| | Li, Jing-Meng [VerfasserIn] |
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| | Zhu, Xian-Bo [VerfasserIn] |
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| | Zhang, Jing [VerfasserIn] |
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| | Fu, Wan-Lei [VerfasserIn] |
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| | Huang, Zan-Sheng [VerfasserIn] |
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| | Herth, Felix [VerfasserIn] |
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| | Fan, Ye [VerfasserIn] |
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| Titel: | Mediastinal cryobiopsy for pathological diagnosis of fibrosing mediastinitis-associated pulmonary hypertension |
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| Verf.angabe: | Ya-Ting You, Hao Zuo, Jing-Meng Li, Xian-Bo Zhu, Jing Zhang, Wan-Lei Fu, Zan-Sheng Huang, Felix J. Herth, Ye Fan |
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| E-Jahr: | 2024 |
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| Jahr: | February 2024 |
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| Umfang: | 5 S. |
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| Illustrationen: | Illustrationen |
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| Fussnoten: | Online veröffentlicht: 25. Januar 2024 ; Gesehen am 11.06.2024 |
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| Titel Quelle: | Enthalten in: Respiration |
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| Ort Quelle: | Basel : Karger, 1944 |
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| Jahr Quelle: | 2024 |
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| Band/Heft Quelle: | 103(2024), 2 vom: Feb., Seite 95-99 |
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| ISSN Quelle: | 1423-0356 |
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| Abstract: | Introduction: Fibrosing mediastinitis is a benign but fatal disorder characterized by the proliferation of fibrous tissue in the mediastinum, causing encasement of mediastinal organs and extrinsic compression of adjacent bronchovascular structures. FM-associated pulmonary hypertension (FM-PH) is a serious complication of FM, resulting from the external compression of lung vessels. Pathologic assessment is important for etiologic diagnosis and effective treatment of this disease. Case Presentation: A 59-year-old male patient presented at our hospital and was diagnosed with FM-PH. He declined surgical biopsy that is the reference standard for pathologic assessment, in consideration of the potential risks. Therefore, an endobronchial ultrasound examination was performed, which identified the subcarinal lesion. Under ultrasound guidance, four needle aspirations were carried out, followed by one cryobiopsy. Histopathological examination of transbronchial needle aspiration specimens was inconclusive, while samples from cryobiopsy suggested a diagnosis of idiopathic FM. Further immunophenotyping demonstrated the infiltration of lymphocytes, macrophages, and FOXP3-positive cells in FM-PH. Conclusion: Mediastinal cryobiopsy might be a novel and safe option for FM-PH patients who are unwilling or unsuitable for surgical procedure. |
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| DOI: | doi:10.1159/000535395 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: https://doi.org/10.1159/000535395 |
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| | DOI: https://doi.org/10.1159/000535395 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| K10plus-PPN: | 1891047868 |
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| Verknüpfungen: | → Zeitschrift |
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Mediastinal cryobiopsy for pathological diagnosis of fibrosing mediastinitis-associated pulmonary hypertension / You, Ya-Ting [VerfasserIn]; February 2024 (Online-Ressource)
