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| Verfasst von: | Afting, Cassian [VerfasserIn]  |
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| | Mainik, Philipp [VerfasserIn] |
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| | Vázquez-Martel, Clara [VerfasserIn] |
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| | Abele, Tobias [VerfasserIn] |
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| | Kaul, Verena [VerfasserIn] |
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| | Kale, Girish [VerfasserIn] |
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| | Göpfrich, Kerstin [VerfasserIn] |
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| | Lemke, Steffen [VerfasserIn] |
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| | Blasco, Eva [VerfasserIn] |
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| | Wittbrodt, Joachim [VerfasserIn] |
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| Titel: | Minimal-invasive 3D laser printing of microimplants in organismo |
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| Verf.angabe: | Cassian Afting, Philipp Mainik, Clara Vazquez-Martel, Tobias Abele, Verena Kaul, Girish Kale, Kerstin Göpfrich, Steffen Lemke, Eva Blasco, and Joachim Wittbrodt |
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| E-Jahr: | 2024 |
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| Jahr: | August 14, 2024 |
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| Umfang: | 11 S. |
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| Illustrationen: | Illustrationen |
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| Fussnoten: | Zuerst veröffentlicht: 12. Juni 2024 ; Gesehen am 25.11.2024 |
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| Titel Quelle: | Enthalten in: Advanced science |
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| Ort Quelle: | Weinheim : Wiley-VCH, 2014 |
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| Jahr Quelle: | 2024 |
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| Band/Heft Quelle: | 11(2024), 30 vom: Aug., Artikel-ID 2401110, Seite 1-11 |
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| ISSN Quelle: | 2198-3844 |
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| Abstract: | Multi-photon 3D laser printing has gathered much attention in recent years as a means of manufacturing biocompatible scaffolds that can modify and guide cellular behavior in vitro. However, in vivo tissue engineering efforts have been limited so far to the implantation of beforehand 3D printed biocompatible scaffolds and in vivo bioprinting of tissue constructs from bioinks containing cells, biomolecules, and printable hydrogel formulations. Thus, a comprehensive 3D laser printing platform for in vivo and in situ manufacturing of microimplants raised from synthetic polymer-based inks is currently missing. Here, a platform for minimal-invasive manufacturing of microimplants directly in the organism is presented by one-photon photopolymerization and multi-photon 3D laser printing. Employing a commercially available elastomeric ink giving rise to biocompatible synthetic polymer-based microimplants, first applicational examples of biological responses to in situ printed microimplants are demonstrated in the teleost fish Oryzias latipes and in embryos of the fruit fly Drosophila melanogaster. This provides a framework for future studies addressing the suitability of inks for in vivo 3D manufacturing. The platform bears great potential for the direct engineering of the intricate microarchitectures in a variety of tissues in model organisms and beyond. |
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| DOI: | doi:10.1002/advs.202401110 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: https://doi.org/10.1002/advs.202401110 |
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| | kostenfrei: Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/advs.202401110 |
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| | DOI: https://doi.org/10.1002/advs.202401110 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Bibliogr. Hinweis: | Forschungsdaten: Afting, Cassian: Minimal-invasive 3D laser printing of microimplants in organismo [data] |
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| Sach-SW: | 3D laser printing |
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| | additive manufacturing |
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| | bioengineering |
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| | Drosophila melanogaster |
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| | microimplants |
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| | Oryzias latipes |
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| | two-photon lithography |
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| K10plus-PPN: | 1892065827 |
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| Verknüpfungen: | → Zeitschrift |
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Minimal-invasive 3D laser printing of microimplants in organismo / Afting, Cassian [VerfasserIn]; August 14, 2024 (Online-Ressource)
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