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Status: Bibliographieeintrag

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Verfasst von:Hartung, Friedrich [VerfasserIn]   i
 Herrmann, Jonas [VerfasserIn]   i
 Kowalewski, Karl-Friedrich [VerfasserIn]   i
 Neuberger, Manuel [VerfasserIn]   i
 Weiß, Christel [VerfasserIn]   i
 Kriegmair, Maximilian [VerfasserIn]   i
 Michel, Maurice Stephan [VerfasserIn]   i
 Ritter, Manuel [VerfasserIn]   i
 Rassweiler-Seyfried, Marie-Claire [VerfasserIn]   i
Titel:Perioperative antibiotic prophylaxis in radical prostatectomy
Titelzusatz:“single-shot” versus multiday regimen
Verf.angabe:Friedrich Otto Hartung, Jonas Herrmann, Karl-Friedrich Kowalewski, Manuel Neuberger, Christel Weiß, Maximilian Christian Kriegmair, Maurice Stephan Michel, Manuel Ritter, Marie-Claire Rassweiler-Seyfried
E-Jahr:2023
Jahr:May 23 2023
Umfang:7 S.
Fussnoten:Im Titel ist "single-shot" in Anführungszeichen geschrieben ; Online veröffentlicht: 14. Dezember 2022 ; Gesehen am 25.06.2024
Titel Quelle:Enthalten in: Urologia internationalis
Ort Quelle:Basel : Karger, 1955
Jahr Quelle:2023
Band/Heft Quelle:107(2023), 5 vom: Mai, Seite 447-453
ISSN Quelle:1423-0399
Abstract:Introduction: Perioperative antibiotic prophylaxis (AP) is common in radical prostatectomy (RP). Yet there is no standard recommendation in international guidelines due to poor evidence. It is of great importance that these perioperative AP are sufficiently checked and systemically validated. The objective of this study was to determine whether a “single-shot” (single-use) perioperative AP yields equivalent results compared to a multiday prophylaxis in RP regarding postoperative wound infections and urinary tract infections. Methods: 376 patients treated by RP at the University Medical Centre Mannheim, from 2014 to 2016, were included in this retrospective study. RP was performed either in a robotic-assisted or open manner. One group received an intravenous dose of perioperative AP with either ciprofloxacin or levofloxacin, continued by an oral dose of AP with ciprofloxacin or levofloxacin until catheter removal, while the other group received a single-shot intravenous perioperative AP with either ciprofloxacin or cefuroxime. Results: There was no significant difference regarding the occurrence of postoperative infections between both AP regimes (p = 0.5). Age, body mass index, and ASA classification did not differ significantly between both groups (p > 0.25). Except for surgery time (p < 0.05), perioperative parameters, such as the preoperative presence of germ-free urine culture, length of hospital stay, catheter time, drain lay time, Gleason score, and TNM stadium, did not differ significantly. Conclusion: The present study shows that perioperative single-shot AP does not entail any disadvantage compared to the multiday AP in terms of postoperative infections after RP.
DOI:doi:10.1159/000527619
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1159/000527619
 Volltext: https://karger.com/uin/article/107/5/447/836277/Perioperative-Antibiotic-Prophylaxis-in-Radical
 DOI: https://doi.org/10.1159/000527619
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1892139863
Verknüpfungen:→ Zeitschrift

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