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Verfasst von:Lütgerath, Constantin [VerfasserIn]   i
 Weiß, Christel [VerfasserIn]   i
 Faulhaber, Jörg [VerfasserIn]   i
 Karsai, Syrus [VerfasserIn]   i
Titel:Comparison of a novel aluminum lactate-based with an aluminum chloride-based antiperspirant in excessive axillary and inguinal perspiration
Titelzusatz:first randomized controlled trial
Verf.angabe:Constantin Lütgerath, Christel Weiß, Jörg Faulhaber, Syrus Karsai
E-Jahr:2022
Jahr:10 December 2022
Umfang:13 S.
Fussnoten:Gesehen am 08.07.2024
Titel Quelle:Enthalten in: Deutsche Dermatologische GesellschaftJournal der Deutschen Dermatologischen Gesellschaft
Ort Quelle:Berlin : Wiley-Blackwell, 2003
Jahr Quelle:2022
Band/Heft Quelle:20(2022), 12 vom: Dez., Seite 1589-1601
ISSN Quelle:1610-0387
Abstract:Background Topical aluminum salts are a commonly used remedy for excessive axillary perspiration. To the contrary, less is known about their anhidrotic potential in the groin. This study sought to compare the anhidrotic efficacy and tolerability of an aluminum chloride-based antiperspirant to an innovative aluminum lactate-based antiperspirant in healthy study participants presenting with excessive axillary and inguinal perspiration. Participants and Methods Fifty participants were enrolled in this open open-labeled, randomized, controlled trial. Following a baseline assessment, efficacy was analyzed at two time points throughout the study period by means of four physiological parameters (pH value, transepidermal water loss, gravimetric analysis, Minor test) and two questionnaires (Dermatology Life Quality Index, Hyperhidrosis Disease Severity Scale). Tolerability was evaluated via symptom diaries. Results Both study preparations were comparably effective in reducing axillary and inguinal perspiration and exhibited increasing effectiveness over time. In both treatment regions, the aluminum lactate-based antiperspirant had a more favorable tolerability profile than the aluminum chloride-based antiperspirant. Conclusions Due to its comparable efficacy and - most noticeably in the groin - superior tolerability, this study supports the use of topical aluminum lactate as a first-line option to control excessive axillary and inguinal perspiration.
DOI:doi:10.1111/ddg.14898
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1111/ddg.14898
 Volltext: http://onlinelibrary.wiley.com/doi/abs/10.1111/ddg.14898
 DOI: https://doi.org/10.1111/ddg.14898
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1894416201
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