Computed diffusion-weighted imaging in patients with transient neurovascular symptoms with and without ischemic infarction

• Verfasst von: Förster, Alex [VerfasserIn]
• Verfasst von: Ramos, Ana [VerfasserIn]
• Verfasst von: Wenz, Holger [VerfasserIn]
• Verfasst von: Groden, Christoph [VerfasserIn]
• Verfasst von: Alonso, Angelika [VerfasserIn]
• Titel: Computed diffusion-weighted imaging in patients with transient neurovascular symptoms with and without ischemic infarction
• Verf.angabe: A. Förster, Ana Ramos, H. Wenz, C. Groden, A. Alonso
• Jahr: 2024
• Umfang: 4 S.
• Illustrationen: Illustrationen
• Fussnoten: Online verfügbar: 1 March 2023 ; Gesehen am 10.07.2024
• Titel Quelle: Enthalten in: Journal of neuroradiology
• Ort Quelle: Issy-les-Moulineaux : Elsevier Masson, 1995
• Jahr Quelle: 2024
• Band/Heft Quelle: 51(2024), 1 vom: Feb., Seite 1-4
• ISSN Quelle: 1773-0406
• DOI: doi:10.1016/j.neurad.2023.02.007
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: cDWI
• Sach-SW: computed DWI
• Sach-SW: Diffusion Magnetic Resonance Imaging
• Sach-SW: Female
• Sach-SW: Humans
• Sach-SW: Infarction
• Sach-SW: Ischemic Attack, Transient
• Sach-SW: Ischemic lesion
• Sach-SW: Male
• Sach-SW: Stroke
• Sach-SW: Transient ischemic attack
• Sach-SW: Transient neurovascular symptoms
• K10plus-PPN: 1895048451

Abstract

PURPOSE: Detection of ischemic lesions in patients with transient neurovascular symptoms is relevant for the estimation of the risk of a subsequent stroke and etiological classification. To improve detection rates, different technical approaches have been used, such as diffusion-weighted imaging (DWI) with high b-values or higher magnetic field strength. Here, we sought to investigate the value of computed DWI (cDWI) with high b-values in these patients. - METHODS: From an MRI report database we identified patients with transient neurovascular symptoms who underwent repeated MRI including DWI. cDWI was calculated with a monoexponential model with high b-values (2000, 3000, and 4000 s/mm2) and compared to the routinely used standard DWI with regard to presence of ischemic lesions and lesion detectability. - RESULT: Overall 33 patients with transient neurovascular symptoms (71 [IQR 57-83.5] years; 21 [63.6%] male) were included. On DWI, acute ischemic lesions were observed in 22 (78.6%). Acute ischemic lesions were observed in 17 (51.5%) patients on initial DWI, and in 26 (78.8%) patients on follow-up DWI. Lesion detectability was rated significantly better on cDWI at 2000s/mm2 compared to standard DWI. In 2 (9.1%) patients, cDWI at 2000s/mm2 revealed an acute ischemic lesion proven on follow-up standard DWI which was not detected with certainty on the initial standard DWI. - CONCLUSION: cDWI might be a valuable addition to routinely acquired standard DWI in patients with transient neurovascular symptoms since its use might result in improved ischemic lesion detection. A b-value of 2000s/mm2 seems most promising for clinical practice.