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| Verfasst von: | Slivka, Jakub Peter [VerfasserIn]  |
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| | Bauer, Chris [VerfasserIn] |
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| | Younsi, Alexander [VerfasserIn] |
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| | Wong, Michelle B. F. [VerfasserIn] |
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| | Chan, Mike K. S. [VerfasserIn] |
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| | Skutella, Thomas [VerfasserIn] |
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| Titel: | Exploring the molecular tapestry |
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| Titelzusatz: | organ-specific peptide and protein ultrafiltrates and their role in therapeutics |
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| Verf.angabe: | Jakub Peter Slivka, Chris Bauer, Alexander Younsi, Michelle B. F. Wong, Mike K. S. Chan and Thomas Skutella |
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| E-Jahr: | 2024 |
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| Jahr: | 1 March 2024 |
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| Umfang: | 24 S. |
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| Illustrationen: | Illustrationen |
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| Fussnoten: | Gesehen am 23.07.2024 |
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| Titel Quelle: | Enthalten in: International journal of molecular sciences |
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| Ort Quelle: | Basel : Molecular Diversity Preservation International, 2000 |
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| Jahr Quelle: | 2024 |
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| Band/Heft Quelle: | 25(2024), 5, Artikel-ID 2863, Seite 1-24 |
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| ISSN Quelle: | 1422-0067 |
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| | 1661-6596 |
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| Abstract: | This study aims to characterize the proteome composition of organ-derived protein extracts from rabbits. Protein isolation was performed using soft homogenization and size exclusion via ultrafiltration. The proteome analysis of the ultrafiltrates was conducted using gel electrophoresis, and the mass spectrometry data were subjected to gene ontology analysis. Proteomic profiling revealed comprehensive protein profiles associated with RNA regulation, fatty acid binding, inflammatory response, oxidative stress, and metabolism. Additionally, our results demonstrate the presence of abundant small proteins, as observed in the mass spectrometry datasets. Small proteins and peptides are crucial in transcription modulation and various biological processes. The protein networks identified in the ultrafiltrates have the potential to enhance and complement biological therapeutic interventions. Data are available via ProteomeXchange with identifier PXD050039. |
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| DOI: | doi:10.3390/ijms25052863 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: https://doi.org/10.3390/ijms25052863 |
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| | kostenfrei: Volltext: https://www.proquest.com/docview/2955550225/abstract/D28B9A82B17E4C18PQ/1 |
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| | DOI: https://doi.org/10.3390/ijms25052863 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | organ specificity |
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| | proteomics |
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| | small proteins |
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| | ultrafiltration |
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| K10plus-PPN: | 1896046118 |
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| Verknüpfungen: | → Zeitschrift |
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Exploring the molecular tapestry / Slivka, Jakub Peter [VerfasserIn]; 1 March 2024 (Online-Ressource)
