Navigation überspringen
Universitätsbibliothek Heidelberg
Status: Bibliographieeintrag

Verfügbarkeit
Standort: ---
Exemplare: ---
heiBIB
 Online-Ressource
Verfasst von:Korosoglou, Grigorios [VerfasserIn]   i
 Sagris, Marios [VerfasserIn]   i
 André, Florian [VerfasserIn]   i
 Steen, Henning [VerfasserIn]   i
 Montenbruck, Moritz [VerfasserIn]   i
 Frey, Norbert [VerfasserIn]   i
 Kelle, Sebastian [VerfasserIn]   i
Titel:Systematic review and meta-analysis for the value of cardiac magnetic resonance strain to predict cardiac outcomes
Verf.angabe:Grigorios Korosoglou, Marios Sagris, Florian André, Henning Steen, Moritz Montenbruck, Norbert Frey & Sebastian Kelle
E-Jahr:2024
Jahr:11 January 2024
Umfang:10 S.
Illustrationen:Illustrationen
Fussnoten:Gesehen am 30.07.2024
Titel Quelle:Enthalten in: Scientific reports
Ort Quelle:[London] : Springer Nature, 2011
Jahr Quelle:2024
Band/Heft Quelle:14(2024), Artikel-ID 1094, Seite 1-10
ISSN Quelle:2045-2322
Abstract:Cardiac magnetic resonance (CMR) is the gold standard for the diagnostic classification and risk stratification in most patients with cardiac disorders. The aim of the present study was to investigate the ability of Strain-encoded MR (SENC) for the prediction of major adverse cardiovascular events (MACE). A systematic review and meta-analysis was performed according to the PRISMA Guidelines, including patients with or without cardiovascular disease and asymptomatic individuals. Myocardial strain by HARP were used as pulse sequences in 1.5 T scanners. Published literature in MEDLINE (PubMed) and Cochrane’s databases were explored before February 2023 for studies assessing the clinical utility of myocardial strain by Harmonic Phase Magnetic Resonance Imaging (HARP), Strain-encoded MR (SENC) or fast-SENC. In total, 8 clinical trials (4 studies conducted in asymptomatic individuals and 4 in patients with suspected or known cardiac disease) were included in this systematic review, while 3 studies were used for our meta-analysis, based on individual patient level data. Kaplan-Meier analysis and Cox proportional hazard models were used, testing the ability of myocardial strain by HARP and SENC/fast-SENC for the prediction of MACE. Strain enabled risk stratification in asymptomatic individuals, predicting MACE and the development of incident heart failure. Of 1332 patients who underwent clinically indicated CMR, including SENC or fast-SENC acquisitions, 19 patients died, 28 experienced non-fatal infarctions, 52 underwent coronary revascularization and 86 were hospitalized due to heart failure during median 22.4 (17.2-28.5) months of follow-up. SENC/fast-SENC, predicted both all-cause mortality and MACE with high accuracy (HR = 3.0, 95% CI = 1.2-7.6, p = 0.02 and HR = 4.1, 95% CI = 3.0-5.5, respectively, p < 0.001). Using hierarchical Cox-proportional hazard regression models, SENC/fast-SENC exhibited incremental value to clinical data and conventional CMR parameters. Reduced myocardial strain predicts of all-cause mortality and cardiac outcomes in symptomatic patients with a wide range of ischemic or non-ischemic cardiac diseases, whereas in asymptomatic individuals, reduced strain was a precursor of incident heart failure.
DOI:doi:10.1038/s41598-023-50835-5
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

kostenfrei: Volltext: https://doi.org/10.1038/s41598-023-50835-5
 kostenfrei: Volltext: https://www.nature.com/articles/s41598-023-50835-5
 DOI: https://doi.org/10.1038/s41598-023-50835-5
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:Cardiology
 Outcomes research
K10plus-PPN:1897053274
Verknüpfungen:→ Zeitschrift

Permanenter Link auf diesen Titel (bookmarkfähig):  https://katalog.ub.uni-heidelberg.de/titel/69238588   QR-Code
zum Seitenanfang