| |  Online-Ressource |
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| Verfasst von: | Leonhardt, Carl-Stephan [VerfasserIn]  |
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| | Niesen, Willem [VerfasserIn] |
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| | Pils, Dietmar [VerfasserIn] |
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| | Angelova, Yoana [VerfasserIn] |
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| | Hankeln, Thomas [VerfasserIn] |
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| | Scheele, Christian [VerfasserIn] |
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| | Hinz, Ulf [VerfasserIn] |
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| | Hackert, Thilo [VerfasserIn] |
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| | Büchler, Markus W. [VerfasserIn] |
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| | Strobel, Oliver [VerfasserIn] |
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| Titel: | Patient reported outcomes of duodenum-preserving pancreatic head resection in chronic pancreatitis |
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| Titelzusatz: | high effectivity is impaired by prolonged non-surgical management |
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| Verf.angabe: | Carl-Stephan Leonhardt, Willem Niesen, Dietmar Pils, Yoana Angelova, Thomas Hank, Christian Scheele, Ulf Hinz, Thilo Hackert, Markus W. Buechler, Oliver Strobel |
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| E-Jahr: | 2024 |
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| Jahr: | January 2024 |
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| Umfang: | 10 S. |
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| Fussnoten: | Gesehen am 12.08.2024 |
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| Titel Quelle: | Enthalten in: HPB |
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| Ort Quelle: | [London] : Elsevier, 1999 |
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| Jahr Quelle: | 2024 |
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| Band/Heft Quelle: | 26(2024), 1, Seite 73-82 |
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| ISSN Quelle: | 1477-2574 |
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| Abstract: | Background: Chronic pancreatitis (CP) causes suffering and socioeconomic burden. This study evaluated perioperative results and patient-reported outcomes (PRO) in CP patients treated with duodenumpreserving pancreatic head resection (DPPHR).Methods: Data were analyzed of CP patients undergoing DPPHR between 01/2001-10/2014. PROs were measured using a specifically designed questionnaire and the EORTC QLQ-C30/PAN26. Associations between treatment variables and PROs were examined.Results: Of 332 patients who received DPPHR, most (n = 251, 75.6%) underwent the Berne modification. Surgical morbidity was 21.5% (n = 71) and 90-day mortality 1.5% (n = 5). Median follow-up was 79.9 months, 5-year survival 90.5%, and 1.8% of patients developed pancreatic cancer. Of 283 patients alive, 178 (62.9%) returned questionnaires. Referral for surgery was self-initiated (38.0% of cases), by gastroenterologists (27.5%) and by general practitioners (21.1%). QoL improved in 78.7% of patients, remained stable in 12.1%, and worsened in 9.1%. Median Izbicki scores decreased from 90 to 5 points after surgery (p < 0.0001). Time from diagnosis to DPPHR was an independent, proportional predictor of a higher postoperative Izbicki score (p = 0.04).Conclusion: DPPHR is an effective, safe treatment for CP. A delay in surgery decreases surgical effectivity, hence CP patients should be referred to surgery early to ensure satisfactory outcomes. |
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| DOI: | doi:10.1016/j.hpb.2023.10.002 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1016/j.hpb.2023.10.002 |
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| | DOI: https://doi.org/10.1016/j.hpb.2023.10.002 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | BEGER |
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| | EARLY-SURGERY |
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| | EORTC QLQ-C30 |
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| | FOLLOW-UP |
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| | GUIDELINES |
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| | INTERNATIONAL STUDY-GROUP |
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| | PAIN |
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| | PANCREATICODUODENECTOMY |
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| | QUALITY-OF-LIFE |
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| | RANDOMIZED-TRIAL |
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| K10plus-PPN: | 1898470979 |
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| Verknüpfungen: | → Zeitschrift |
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Patient reported outcomes of duodenum-preserving pancreatic head resection in chronic pancreatitis / Leonhardt, Carl-Stephan [VerfasserIn]; January 2024 (Online-Ressource)
