Status: Bibliographieeintrag
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| Verfasst von: | Angelova, Assia L. [VerfasserIn]  |
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| | Rommelaere, Jean [VerfasserIn] |
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| | Ungerechts, Guy [VerfasserIn] |
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| Titel: | The complex role of infectious agents in human cutaneous T-cell lymphoma pathogenesis |
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| Titelzusatz: | from candidate etiological factors to potential therapeutics |
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| Verf.angabe: | Assia Angelova, Jean Rommelaere and Guy Ungerechts |
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| E-Jahr: | 2024 |
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| Jahr: | 20. Februar 2024 |
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| Umfang: | 11 S. |
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| Fussnoten: | Gesehen am 14.08.2024 |
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| Titel Quelle: | Enthalten in: Pathogens |
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| Ort Quelle: | Basel : MDPI, 2012 |
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| Jahr Quelle: | 2024 |
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| Band/Heft Quelle: | 13(2024), 3, Artikel-ID 184, Seite 1-11 |
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| ISSN Quelle: | 2076-0817 |
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| Abstract: | Cutaneous T-cell lymphoma (CTCL) is a devastating, potentially fatal T-lymphocyte malignancy affecting the skin. Despite all efforts, the etiology of this disease remains unknown. Infectious agents have long been suspected as factors or co-factors in CTCL pathogenesis. This review deals with the panel of bacterial and viral pathogens that have been investigated so far in an attempt to establish a potential link between infection/carriage and CTCL development. A special focus is given to a recently discovered human protoparvovirus, namely the cutavirus (CutaV), which has emerged as a plausible CTCL etiological agent. Available evidence in support of this hypothesis as well as alternative interpretations and uncertainties raised by some conflicting data are discussed. The complexity and multifacetedness of the Parvoviridae family of viruses are illustrated by presenting another protoparvovirus, the rat H-1 parvovirus (H-1PV). H-1PV belongs to the same genus as the CutaV but carries considerable potential for therapeutic applications in cutaneous lymphoma. |
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| DOI: | doi:10.3390/pathogens13030184 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: https://doi.org/10.3390/pathogens13030184 |
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| | kostenfrei: Volltext: https://www.mdpi.com/2076-0817/13/3/184 |
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| | DOI: https://doi.org/10.3390/pathogens13030184 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Parvoviridae |
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| | cutaneous T-cell lymphoma |
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| | cutavirus |
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| | infectious etiology |
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| | oncolytic H-1 parvovirus |
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| K10plus-PPN: | 1898664080 |
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| Verknüpfungen: | → Zeitschrift |
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¬The¬ complex role of infectious agents in human cutaneous T-cell lymphoma pathogenesis / Angelova, Assia L. [VerfasserIn]; 20. Februar 2024 (Online-Ressource)
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