Advanced diffusion-weighted imaging sequences for breast MRI

• Verfasst von: Hausmann, Daniel [VerfasserIn]
• Verfasst von: Todorski, Inga [VerfasserIn]
• Verfasst von: Pindur, Alexandra [VerfasserIn]
• Verfasst von: Weiland, Elisabeth [VerfasserIn]
• Verfasst von: Benkert, Thomas [VerfasserIn]
• Verfasst von: Bosshard, Lars [VerfasserIn]
• Verfasst von: Prummer, Michael [VerfasserIn]
• Verfasst von: Kubik-Huch, Rahel A. [VerfasserIn]
• Titel: Advanced diffusion-weighted imaging sequences for breast MRI
• Titelzusatz: comprehensive comparison of improved sequences and ultra-high B-values to identify the optimal combination
• Verf.angabe: Daniel Hausmann, Inga Todorski, Alexandra Pindur, Elisabeth Weiland, Thomas Benkert, Lars Bosshard, Michael Prummer and Rahel A. Kubik-Huch
• E-Jahr: 2023
• Jahr: 7 February 2023
• Umfang: 14 S.
• Illustrationen: Illustrationen
• Fussnoten: Gesehen am 15.08.2024
• Titel Quelle: Enthalten in: Diagnostics
• Ort Quelle: Basel : MDPI, 2011
• Jahr Quelle: 2023
• Band/Heft Quelle: 13(2023), 4, Artikel-ID 607, Seite 1-14
• ISSN Quelle: 2075-4418
• DOI: doi:10.3390/diagnostics13040607
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: artifacts
• Sach-SW: breast
• Sach-SW: breast cancer
• Sach-SW: diffusion-weighted imaging
• Sach-SW: image quality
• Sach-SW: magnetic resonance imaging
• Sach-SW: noise reduction
• K10plus-PPN: 1898764689

Abstract

This study investigated the image quality and choice of ultra-high b-value of two DWI breast-MRI research applications. The study cohort comprised 40 patients (20 malignant lesions). In addition to s-DWI with two m-b-values (b50 and b800) and three e-b-values (e-b1500, e-b2000, and e-b2500), z-DWI and IR m-b1500 DWI were applied. z-DWI was acquired with the same measured b-values and e-b-values as the standard sequence. For IR m-b1500 DWI, b50 and b1500 were measured, and e-b2000 and e-b2500 were mathematically extrapolated. Three readers used Likert scales to independently analyze all ultra-high b-values (b1500-b2500) for each DWI with regards to scan preference and image quality. ADC values were measured in all 20 lesions. z-DWI was the most preferred (54%), followed by IR m-b1500 DWI (46%). b1500 was significantly preferred over b2000 for z-DWI and IR m-b1500 DWI (p = 0.001 and p = 0.002, respectively). Lesion detection was not significantly different among sequences or b-values (p = 0.174). There were no significant differences in measured ADC values within lesions between s-DWI (ADC: 0.97 [±0.09] × 10−3 mm2/s) and z-DWI (ADC: 0.99 [±0.11] × 10−3 mm2/s; p = 1.000). However, there was a trend toward lower values in IR m-b1500 DWI (ADC: 0.80 [±0.06] × 10−3 mm2/s) than in s-DWI (p = 0.090) and z-DWI (p = 0.110). Overall, image quality was superior and there were fewer image artifacts when using the advanced sequences (z-DWI + IR m-b1500 DWI) compared with s-DWI. Considering scan preferences, we found that the optimal combination was z-DWI with a calculated b1500, especially regarding examination time.