| |  Online-Ressource |
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| Verfasst von: | Barwig, Chantal [VerfasserIn]  |
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| | Sonn, Annabelle [VerfasserIn] |
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| | Spratte, Tobias [VerfasserIn] |
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| | Mishra, Ankit [VerfasserIn] |
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| | Blasco, Eva [VerfasserIn] |
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| | Selhuber-Unkel, Christine [VerfasserIn] |
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| | Pashapour, Sadaf [VerfasserIn] |
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| Titel: | Two-photon direct laser writing of pNIPAM actuators in microchannels for dynamic microfluidics |
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| Verf.angabe: | Chantal Barwig, Annabelle Sonn, Tobias Spratte, Ankit Mishra, Eva Blasco, Christine Selhuber-Unkel, and Sadaf Pashapour |
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| E-Jahr: | 2024 |
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| Jahr: | July 2024 |
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| Umfang: | 11 S. |
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| Illustrationen: | Illustrationen |
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| Fussnoten: | Online veröffentlicht: 15. April 2024 ; Gesehen am 16.08.2024 |
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| Titel Quelle: | Enthalten in: Advanced intelligent systems |
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| Ort Quelle: | Weinheim : Wiley-VCH Verlag GmbH & Co. KGaA, 2019 |
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| Jahr Quelle: | 2024 |
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| Band/Heft Quelle: | 6(2024), 7 vom: Juli, Artikel-ID 2300829, Seite 1-11 |
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| ISSN Quelle: | 2640-4567 |
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| Abstract: | Microfluidic tools enable to investigate and manipulate various chemical and biological processes at small scales. As a result, it finds widespread applications in lab-on-chip devices, drug delivery systems, or miniaturized cell cultures. However, microfluidic devices are still limited in their flexibility and are often designed to fulfill a single functionality. Moreover, technologies to introduce dynamic functionalities with high precision and at high resolution after the development of a continuous phase microfluidic chip remain scarce. Herein, two-photon polymerization direct laser writing is introduced as a suitable approach to equip continuous phase microfluidic chips with structurally defined thermoresponsive poly(N-isopropyl-acrylamide) (pNIPAM) microactuators. Harnessing the lower critical phase transition temperature of pNIPAM, and upon controlling specific design parameters, the efficient catch and release of polystyrene beads of different sizes using a pNIPAM micropillar brush array is demonstrated. Moreover, a biocompatible pNIPAM microgripper array is designed to subsequently capture and release differently sized (single) cell populations. Overall, the method offers great flexibility and a high degree of freedom toward the fabrication of dynamic microfluidic devices with great adaptability to experimental conditions in real time. |
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| DOI: | doi:10.1002/aisy.202300829 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1002/aisy.202300829 |
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| | Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/aisy.202300829 |
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| | DOI: https://doi.org/10.1002/aisy.202300829 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | direct laser writing |
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| | dynamic microfluidics |
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| | soft microactuators |
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| | thermoresponsive hydrogels |
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| | two-photon polymerization |
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| K10plus-PPN: | 1899048103 |
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| Verknüpfungen: | → Zeitschrift |
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Two-photon direct laser writing of pNIPAM actuators in microchannels for dynamic microfluidics / Barwig, Chantal [VerfasserIn]; July 2024 (Online-Ressource)
