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| Verfasst von: | Hebebrand, Johannes [VerfasserIn]  |
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| | Seitz, Jochen [VerfasserIn] |
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| | Föcker, Manuel [VerfasserIn] |
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| | Viersen, Hanna Preuss-van [VerfasserIn] |
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| | Huss, Michael [VerfasserIn] |
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| | Bühren, Katharina [VerfasserIn] |
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| | Dahmen, Brigitte [VerfasserIn] |
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| | Becker, Katja [VerfasserIn] |
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| | Weber, Linda [VerfasserIn] |
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| | Correll, Christoph U. [VerfasserIn] |
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| | Jaite, Charlotte [VerfasserIn] |
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| | Egberts, Karin [VerfasserIn] |
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| | Romanos, Marcel [VerfasserIn] |
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| | Ehrlich, Stefan [VerfasserIn] |
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| | Seidel, Maria [VerfasserIn] |
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| | Roessner, Veit [VerfasserIn] |
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| | Fleischhaker, Christian [VerfasserIn] |
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| | Möhler, Eva [VerfasserIn] |
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| | Hahn, Freia [VerfasserIn] |
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| | Kaess, Michael [VerfasserIn] |
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| | Legenbauer, Tanja [VerfasserIn] |
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| | Hagmann, Daniela [VerfasserIn] |
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| | Renner, Tobias J. [VerfasserIn] |
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| | Schulze, Ulrike M. E. [VerfasserIn] |
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| | Thiemann, Ulf [VerfasserIn] |
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| | Wessing, Ida [VerfasserIn] |
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| | Antony, Gisela [VerfasserIn] |
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| | Herpertz-Dahlmann, Beate [VerfasserIn] |
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| | Matthews, Abigail [VerfasserIn] |
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| | Peters, Triinu [VerfasserIn] |
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| Titel: | Premorbid body weight predicts weight loss in both anorexia nervosa and atypical anorexia nervosa |
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| Titelzusatz: | further support for a single underlying disorder |
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| Verf.angabe: | Johannes Hebebrand PhD, Jochen Seitz PhD, Manuel Föcker PhD, Hanna Preuss-van Viersen PhD, Michael Huss PhD, Katharina Bühren PhD, Brigitte Dahmen PhD, Katja Becker PhD, Linda Weber PhD, Christoph U. Correll PhD, Charlotte Jaite PhD, Karin Egberts PhD, Marcel Romanos PhD, Stefan Ehrlich PhD, Maria Seidel PhD, Veit Roessner PhD, Christian Fleischhaker PhD, Eva Möhler PhD, Freia Hahn PhD, Michael Kaess PhD, Tanja Legenbauer PhD, Daniela Hagmann PhD, Tobias J. Renner PhD, Ulrike M.E. Schulze PhD, Ulf Thiemann PhD, Ida Wessing, Gisela Antony, Beate Herpertz-Dahlmann PhD, Abigail Matthews PhD, Triinu Peters PhD |
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| E-Jahr: | 2024 |
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| Jahr: | April 2024 |
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| Umfang: | 16 S. |
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| Illustrationen: | Illustrationen |
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| Fussnoten: | Zuerst veröffentlicht: 25. März 2024 ; Gesehen am 13.09.2024 |
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| Titel Quelle: | Enthalten in: The international journal of eating disorders |
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| Ort Quelle: | New York, NY : Wiley, 1981 |
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| Jahr Quelle: | 2024 |
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| Band/Heft Quelle: | 57(2024), 4 vom: Apr., Seite 967-982 |
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| ISSN Quelle: | 1098-108X |
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| Abstract: | Objective: For adolescents, DSM-5 differentiates anorexia nervosa (AN) and atypical AN with the 5th BMI-centile-for-age. We hypothesized that the diagnostic weight cut-off yields (i) lower weight loss in atypical AN and (ii) discrepant premorbid BMI distributions between the two disorders. Prior studies demonstrate that premorbid BMI predicts admission BMI and weight loss in patients with AN. We explore these relationships in atypical AN. Method: Based on admission BMI-centile < or ≥5th, participants included 411 female adolescent inpatients with AN and 49 with atypical AN from our registry study. Regression analysis and t-tests statistically addressed our hypotheses and exploratory correlation analyses compared interrelationships between weight loss, admission BMI, and premorbid BMI in both disorders. Results: Weight loss in atypical AN was 5.6 kg lower than in AN upon adjustment for admission age, admission height, premorbid weight and duration of illness. Premorbid BMI-standard deviation scores differed by almost one between both disorders. Premorbid BMI and weight loss were strongly correlated in both AN and atypical AN. Discussion: Whereas the weight cut-off induces discrepancies in premorbid weight and adjusted weight loss, AN and atypical AN overall share strong weight-specific interrelationships that merit etiological consideration. Epidemiological and genetic associations between AN and low body weight may reflect a skewed premorbid BMI distribution. In combination with prior findings for similar psychological and medical characteristics in AN and atypical AN, our findings support a homogenous illness conceptualization. We propose that diagnostic subcategorization based on premorbid BMI, rather than admission BMI, may improve clinical validity. Public significance: Because body weights of patients with AN must drop below the 5th BMI-centile per DSM-5, they will inherently require greater weight loss than their counterparts with atypical AN of the same sex, age, height and premorbid weight. Indeed, patients with atypical AN had a 5.6 kg lower weight loss after controlling for these variables. In comparison to the reference population, we found a lower and higher mean premorbid weight in patients with AN and atypical AN, respectively. Considering previous psychological and medical comparisons showing little differences between AN and atypical AN, we view a single disorder as the most parsimonious explanation. Etiological models need to particularly account for the strong relationship between weight loss and premorbid body weight. |
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| DOI: | doi:10.1002/eat.24189 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: https://doi.org/10.1002/eat.24189 |
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| | kostenfrei: Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/eat.24189 |
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| | DOI: https://doi.org/10.1002/eat.24189 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | 5th BMI-for-age centile |
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| | admission weight |
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| | diagnostic classification |
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| | premorbid weight |
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| | starvation |
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| | weight criterion |
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| | weight loss |
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| K10plus-PPN: | 1902525205 |
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| Verknüpfungen: | → Zeitschrift |
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Premorbid body weight predicts weight loss in both anorexia nervosa and atypical anorexia nervosa / Hebebrand, Johannes [VerfasserIn]; April 2024 (Online-Ressource)
