| Online-Ressource |
Verfasst von: | Madrid, Julian [VerfasserIn]  |
| Agarwal, Prerana [VerfasserIn]  |
| Müller-Peltzer, Katharina [VerfasserIn]  |
| Askani, Marvin [VerfasserIn]  |
| Benning, Leo [VerfasserIn]  |
| Selig, Mischa [VerfasserIn]  |
| Diehl, Philipp [VerfasserIn]  |
| Kalbhenn, Johannes [VerfasserIn]  |
| Trummer, Georg [VerfasserIn]  |
| Utzolino, Stefan [VerfasserIn]  |
| Wengenmayer, Tobias [VerfasserIn]  |
| Busch, Hans-Jörg [VerfasserIn]  |
| Stolz, Daiana [VerfasserIn]  |
| Rieg, Siegbert [VerfasserIn]  |
| Panning, Marcus [VerfasserIn]  |
| Schlett, Christopher L. [VerfasserIn]  |
| Bamberg, Fabian [VerfasserIn]  |
| Askani, Esther Adele [VerfasserIn]  |
Titel: | Vaccination protects against acute respiratory distress syndrome (ARDS) in hospitalized patients with COVID-19 |
Verf.angabe: | Julian Madrid, Prerana Agarwal, Katharina Müller-Peltzer, Marvin Askani, Leo Benning, Mischa Selig, Philipp Diehl, Johannes Kalbhenn, Georg Trummer, Stefan Utzolino, Tobias Wengenmayer, Hans-Jörg Busch, Daiana Stolz, Siegbert Rieg, Marcus Panning, Christopher L. Schlett, Fabian Bamberg, Esther Askani |
E-Jahr: | 2024 |
Jahr: | 27 January 2024 |
Umfang: | 16 S. |
Fussnoten: | Gesehen am 16.09.2024 |
Titel Quelle: | Enthalten in: Clinical and experimental medicine |
Ort Quelle: | Milano : Springer, 2001 |
Jahr Quelle: | 2024 |
Band/Heft Quelle: | 24(2024), 1, Artikel-ID 21, Seite 1-16 |
ISSN Quelle: | 1591-9528 |
Abstract: | This study aimed to analyze the effect of COVID-19 vaccination on the occurrence of ARDS in hospitalized COVID-19 patients. The study population of this retrospective, single-center cohort study consisted of hospitalized COVID-19 patients with known vaccination status and chest computed tomography imaging between July 2021 and February 2022. The impact of vaccination on ARDS in COVID-19 patients was assessed through logistic regression adjusting for demographic differences and confounding factors with statistical differences determined using confidence intervals and effect sizes. A total of 167 patients (69% male, average age 58 years, 95% CI [55; 60], 42% fully vaccinated) were included in the data analysis. Vaccinated COVID-19 patients had a reduced relative risk (RR) of developing ARDS (RR: 0.40, 95% CI [0.21; 0.62]). Consequently, non-vaccinated hospitalized patients had a 2.5-fold higher probability of developing ARDS. This risk reduction persisted after adjusting for several confounding variables (RR: 0.64, 95% CI [0.29; 0.94]) in multivariate analysis. The protective effect of COVID-19 vaccination increased with ARDS severity (RR: 0.61, 95% CI [0.37; 0.92]). Particularly, patients under 60 years old were at risk for ARDS onset and seemed to benefit from COVID-19 vaccination (RR: 0.51, 95% CI [0.20; 0.90]). COVID-19 vaccination showed to reduce the risk of ARDS occurrence in hospitalized COVID-19 patients, with a particularly strong effect in patients under 60 years old and those with more severe ARDS. |
DOI: | doi:10.1007/s10238-023-01293-w |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: https://doi.org/10.1007/s10238-023-01293-w |
| kostenfrei: Volltext: https://link.springer.com/article/10.1007/s10238-023-01293-w |
| DOI: https://doi.org/10.1007/s10238-023-01293-w |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | ARDS |
| COVID-19 |
| Hospitalization |
| Vaccination |
K10plus-PPN: | 1902599772 |
Verknüpfungen: | → Zeitschrift |
Vaccination protects against acute respiratory distress syndrome (ARDS) in hospitalized patients with COVID-19 / Madrid, Julian [VerfasserIn]; 27 January 2024 (Online-Ressource)