Anterior segment complications following intravitreal injection

• Verfasst von: Mackenbrock, Lars [VerfasserIn]
• Verfasst von: Auffarth, Gerd U. [VerfasserIn]
• Verfasst von: Albrecht, Michael [VerfasserIn]
• Verfasst von: Naujokaitis, Tadas [VerfasserIn]
• Verfasst von: Kessler, Lucy Joanne [VerfasserIn]
• Verfasst von: Mayer, Christian [VerfasserIn]
• Verfasst von: Khoramnia, Ramin [VerfasserIn]
• Titel: Anterior segment complications following intravitreal injection
• Paralleltitel: Vorderabschnittskomplikationen nach intravitrealer Injektion
• Verf.angabe: Lars H.B. Mackenbrock, Gerd U. Auffarth, Michael Albrecht, Tadas Naujokaitis, Lucy J. Kessler, Christian S. Mayer, Ramin Khoramnia
• E-Jahr: 2024
• Jahr: 15. August 2024
• Umfang: 6 S.
• Fussnoten: Gesehen am 18.09.2024
• Titel Quelle: Enthalten in: Klinische Monatsblätter für Augenheilkunde
• Ort Quelle: Stuttgart : Thieme, 1980
• Jahr Quelle: 2024
• Band/Heft Quelle: 241(2024), 8, Seite 917-922
• ISSN Quelle: 1439-3999
• DOI: doi:10.1055/a-2349-2224
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1902915577

Abstract

Intravitreal injections (IVI s) have gained increased popularity in the past decades and are used to treat a multitude of ailments. In 2010, the total number of IVI s surpassed the number of cataract surgeries performed, making it the most common procedure in ophthalmology. As the number of injections increases, so does the number of injected-related complications. While complications in the posterior segment, such as retinal detachment or endophthalmitis, are detrimental to visual function and have therefore been well documented, IVI s can also lead to complications in the anterior segment. These include hyphema, inflammation of the sterile anterior segment (incidence rate of 0.05 to 1.1% depending on the drug), implant migration with corneal decompensation (incidence rate of 0.43%), iatrogenic lens damage (incidence rate of 0.07%), accelerated cataract formation (up to 50% for steroids and 10.9% for anti-VEGF), and an increased complication rate during subsequent cataract surgery (up to 4% per IVI). Most of these complications occur immediately and have a good prognosis if treated correctly. However, the increased risk of complications during subsequent surgery demonstrates that IVI s can also have long-term complications, a topic that needs to be explored further in future research projects.