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| Verfasst von: | Mulet, Alba [VerfasserIn]  |
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| | Núñez-Gil, Iván J. [VerfasserIn] |
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| | Carbonell, Juan Antonio [VerfasserIn] |
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| | Soriano, Joan B. [VerfasserIn] |
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| | Viana-Llamas, María C. [VerfasserIn] |
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| | Raposeiras-Roubin, Sergio [VerfasserIn] |
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| | Romero, Rodolfo [VerfasserIn] |
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| | Alfonso-Rodríguez, Emilio [VerfasserIn] |
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| | Uribarri, Aitor [VerfasserIn] |
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| | Feltes, Gisela [VerfasserIn] |
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| | Becerra-Muñoz, Victor M. [VerfasserIn] |
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| | Santoro, Francesco [VerfasserIn] |
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| | Pepe, Martino [VerfasserIn] |
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| | Castro-Mejía, Alex F. [VerfasserIn] |
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| | Chipayo, David [VerfasserIn] |
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| | Corbi-Pascual, Miguel [VerfasserIn] |
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| | López-Pais, Javier [VerfasserIn] |
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| | Vedia, Oscar [VerfasserIn] |
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| | Manzone, Edoardo [VerfasserIn] |
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| | Molina-Romera, Germán [VerfasserIn] |
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| | Espejo-Paeres, Carolina [VerfasserIn] |
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| | López-Masjuan, Álvaro [VerfasserIn] |
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| | Velicki, Lazar [VerfasserIn] |
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| | Fernández-Ortiz, Antonio [VerfasserIn] |
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| | El-Battrawy, Ibrahim [VerfasserIn] |
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| | Signes-Costa, Jaime [VerfasserIn] |
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| Titel: | Clinical profile and determinants of mortality in patients with interstitial lung disease admitted for COVID-19 |
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| Verf.angabe: | Alba Mulet, Iván J. Núñez-Gil, Juan Antonio Carbonell, Joan B. Soriano, María C. Viana-Llamas, Sergio Raposeiras-Roubin, Rodolfo Romero, Emilio Alfonso-Rodríguez, Aitor Uribarri, Gisela Feltes, Victor M. Becerra-Muñoz, Francesco Santoro, Martino Pepe, Alex F. Castro-Mejía, David Chipayo, Miguel Corbi-Pascual, Javier López-Pais, Oscar Vedia, Edoardo Manzone, Germán Molina-Romera, Carolina Espejo-Paeres, Álvaro López-Masjuan, Lazar Velicki, Antonio Fernández-Ortiz, Ibrahim El-Battrawy, Jaime Signes-Costa, on behalf of HOPE Team |
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| E-Jahr: | 2023 |
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| Jahr: | 2 June 2023 |
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| Umfang: | 9 S. |
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| Fussnoten: | Gesehen am 30.09.2024 |
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| Titel Quelle: | Enthalten in: Journal of Clinical Medicine |
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| Ort Quelle: | Basel : MDPI, 2012 |
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| Jahr Quelle: | 2023 |
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| Band/Heft Quelle: | 12(2023), 11, Artikel-ID 3821, Seite 1-9 |
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| ISSN Quelle: | 2077-0383 |
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| Abstract: | Background: Concern has risen about the effects of COVID-19 in interstitial lung disease (ILD) patients. The aim of our study was to determine clinical characteristics and prognostic factors of ILD patients admitted for COVID-19. Methods: Ancillary analysis of an international, multicenter COVID-19 registry (HOPE: Health Outcome Predictive Evaluation) was performed. The subgroup of ILD patients was selected and compared with the rest of the cohort. Results: A total of 114 patients with ILDs were evaluated. Mean ± SD age was 72.4 ± 13.6 years, and 65.8% were men. ILD patients were older, had more comorbidities, received more home oxygen therapy and more frequently had respiratory failure upon admission than non-ILD patients (all p < 0.05). In laboratory findings, ILD patients more frequently had elevated LDH, C-reactive protein, and D-dimer levels (all p < 0.05). A multivariate analysis showed that chronic kidney disease and respiratory insufficiency on admission were predictors of ventilatory support, and that older age, kidney disease and elevated LDH were predictors of death. Conclusions: Our data show that ILD patients admitted for COVID-19 are older, have more comorbidities, more frequently require ventilatory support and have higher mortality than those without ILDs. Older age, kidney disease and LDH were independent predictors of mortality in this population. |
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| DOI: | doi:10.3390/jcm12113821 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: https://doi.org/10.3390/jcm12113821 |
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| | kostenfrei: Volltext: https://www.mdpi.com/2077-0383/12/11/3821 |
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| | DOI: https://doi.org/10.3390/jcm12113821 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | COVID-19 |
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| | interstitial lung diseases |
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| | mortality |
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| | ventilatory support |
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| K10plus-PPN: | 1903774012 |
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| Verknüpfungen: | → Zeitschrift |
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Clinical profile and determinants of mortality in patients with interstitial lung disease admitted for COVID-19 / Mulet, Alba [VerfasserIn]; 2 June 2023 (Online-Ressource)
