| |  Online-Ressource |
|---|
| Verfasst von: | Song, Yunhe [VerfasserIn]  |
|---|
| | Li, Fei [VerfasserIn] |
|---|
| | Chong, Rachel S. [VerfasserIn] |
|---|
| | Wang, Wei [VerfasserIn] |
|---|
| | Ran, An Ran [VerfasserIn] |
|---|
| | Lin, Fengbin [VerfasserIn] |
|---|
| | Wang, Peiyuan [VerfasserIn] |
|---|
| | Wang, Zhenyu [VerfasserIn] |
|---|
| | Jiang, Jingwen [VerfasserIn] |
|---|
| | Kong, Kangjie [VerfasserIn] |
|---|
| | Jin, Ling [VerfasserIn] |
|---|
| | Chen, Meiling [VerfasserIn] |
|---|
| | Sun, Jian [VerfasserIn] |
|---|
| | Wang, Deming [VerfasserIn] |
|---|
| | Tham, Clement C. [VerfasserIn] |
|---|
| | Lam, Dennis S. C. [VerfasserIn] |
|---|
| | Zangwill, Linda M. [VerfasserIn] |
|---|
| | Weinreb, Robert N. [VerfasserIn] |
|---|
| | Aung, Tin [VerfasserIn] |
|---|
| | Jonas, Jost B. [VerfasserIn] |
|---|
| | Ohno-Matsui, Kyoko [VerfasserIn] |
|---|
| | Cheng, Ching-Yu [VerfasserIn] |
|---|
| | Bressler, Neil M. [VerfasserIn] |
|---|
| | Sun, Xiaodong [VerfasserIn] |
|---|
| | Cheung, Carol Y. [VerfasserIn] |
|---|
| | Chen, Shida [VerfasserIn] |
|---|
| | Zhang, Xiulan [VerfasserIn] |
|---|
| Titel: | High myopia normative database of peripapillary retinal nerve fiber layer thickness to detect myopic glaucoma in a Chinese population |
|---|
| Verf.angabe: | Yunhe Song, MD, PhD, Fei Li, MD, PhD, Rachel S. Chong, MD, PhD, Wei Wang, MD, PhD, An Ran Ran, MMed, PhD, Fengbin Lin, MD, PhD, Peiyuan Wang, MD, Zhenyu Wang, MD, Jingwen Jiang, MD, Kangjie Kong, MD, Ling Jin, MSc, Meiling Chen, MBBS, Jian Sun, MBBS, Deming Wang, MD, Clement C. Tham, FCOphthHK, Dennis S.C. Lam, MD, PhD, Linda M. Zangwill, PhD, Robert N. Weinreb, MD, Tin Aung, MD, PhD, Jost B. Jonas, MD, Kyoko Ohno-Matsui, MD, PhD, Ching-Yu Cheng, MD, PhD, Neil M. Bressler, MD, Xiaodong Sun, MD, PhD, Carol Y. Cheung, PhD, Shida Chen, MD, PhD, Xiulan Zhang, MD, PhD, for the Glaucoma Suspects with High Myopia Study Group |
|---|
| E-Jahr: | 2023 |
|---|
| Jahr: | December 2023 |
|---|
| Umfang: | 11 S. |
|---|
| Illustrationen: | Illustrationen |
|---|
| Fussnoten: | Online veröffentlicht: 26. Juli 2023, Artikelversion: 17. November 2023 ; Gesehen am 08.10.2024 |
|---|
| Titel Quelle: | Enthalten in: Ophthalmology |
|---|
| Ort Quelle: | Amsterdam [u.a.] : Elsevier, 1978 |
|---|
| Jahr Quelle: | 2023 |
|---|
| Band/Heft Quelle: | 130(2023), 12, Seite 1279-1289 |
|---|
| ISSN Quelle: | 1549-4713 |
|---|
| Abstract: | Purpose - To develop and validate the performance of a high myopia (HM)-specific normative database of peripapillary retinal nerve fiber layer (pRNFL) thickness in differentiating HM from highly myopic glaucoma (HMG). - Design - Cross-sectional multicenter study. - Participants - A total of 1367 Chinese participants (2325 eyes) with nonpathologic HM or HMG were included from 4 centers. After quality control, 1108 eyes from 694 participants with HM were included in the normative database; 459 eyes from 408 participants (323 eyes with HM and 136 eyes with HMG) and 322 eyes from 197 participants (131 eyes with HM and 191 eyes with HMG) were included in the internal and external validation sets, respectively. Only HMG eyes with an intraocular pressure > 21 mmHg were included. - Methods - The pRNFL thickness was measured with swept-source (SS) OCT. Four strategies of pRNFL-specified values were examined, including global and quadrantic pRNFL thickness below the lowest fifth or the lowest first percentile of the normative database. - Main Outcomes Measures - The accuracy, sensitivity, and specificity of the HM-specific normative database for detecting HMG. - Results - Setting the fifth percentile of the global pRNFL thickness as the threshold, using the HM-specific normative database, we achieved an accuracy of 0.93 (95% confidence interval [CI], 0.90-0.95) and 0.85 (95% CI, 0.81-0.89), and, using the first percentile as the threshold, we acheived an accuracy of 0.85 (95% CI, 0.81-0.88) and 0.70 (95% CI, 0.65-0.75) in detecting HMG in the internal and external validation sets, respectively. The fifth percentile of the global pRNFL thickness achieved high sensitivities of 0.75 (95% CI, 0.67-0.82) and 0.75 (95% CI, 0.68-0.81) and specificities of 1.00 (95% CI, 0.99-1.00) and 1.00 (95% CI, 0.97-1.00) in the internal and external validation datasets, respectively. Compared with the built-in database of the OCT device, the HM-specific normative database showed a higher sensitivity and specificity than the corresponding pRNFL thickness below the fifth or first percentile (P < 0.001 for all). - Conclusions - The HM-specific normative database is more capable of detecting HMG eyes than the SS OCT built-in database, which may be an effective tool for differential diagnosis between HMG and HM. - Financial Disclosure(s) - Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article. |
|---|
| DOI: | doi:10.1016/j.ophtha.2023.07.022 |
|---|
| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext: https://doi.org/10.1016/j.ophtha.2023.07.022 |
|---|
| | Volltext: https://www.sciencedirect.com/science/article/pii/S0161642023005183 |
|---|
| | DOI: https://doi.org/10.1016/j.ophtha.2023.07.022 |
|---|
| Datenträger: | Online-Ressource |
|---|
| Sprache: | eng |
|---|
| Sach-SW: | Glaucoma |
|---|
| | High myopia |
|---|
| | Normative database |
|---|
| | OCT |
|---|
| | Retinal nerve fiber layer |
|---|
| K10plus-PPN: | 1905052782 |
|---|
| Verknüpfungen: | → Zeitschrift |
|---|
High myopia normative database of peripapillary retinal nerve fiber layer thickness to detect myopic glaucoma in a Chinese population / Song, Yunhe [VerfasserIn]; December 2023 (Online-Ressource)
