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Verfasst von:Schrottenberg, Christoph von [VerfasserIn]   i
 Lindacker, Maren [VerfasserIn]   i
 Weis, Meike [VerfasserIn]   i
 Büttner, Sylvia [VerfasserIn]   i
 Schaible, Thomas [VerfasserIn]   i
 Boettcher, Michael [VerfasserIn]   i
 Wessel, Lucas [VerfasserIn]   i
 Zahn, Katrin [VerfasserIn]   i
Titel:Long-term evaluation of the sape of the rconstructed daphragm in ptients with left-sided congenital diaphragmatic Hernia using serial chest radiographs and correlation to further complications
Verf.angabe:Christoph von Schrottenberg, Maren Lindacker, Meike Weis, Sylvia Büttner, Thomas Schaible, Michael Boettcher, Lucas M. Wessel and Katrin B. Zahn
E-Jahr:2024
Jahr:22 January 2024
Umfang:16 S.
Fussnoten:Gesehen am 10.10.2024
Titel Quelle:Enthalten in: Journal of Clinical Medicine
Ort Quelle:Basel : MDPI, 2012
Jahr Quelle:2024
Band/Heft Quelle:13(2024), 2, Artikel-ID 620, Seite 1-16
ISSN Quelle:2077-0383
Abstract:Background: Defining risk factors for long-term comorbidities in patients after neonatal repair of congenital diaphragmatic hernia (CDH) is an important cornerstone of the implementation of targeted longitudinal follow-up programs. Methods: This study systematically assessed serial chest radiographs of 89 patients with left-sided CDH throughout a mean follow-up of 8.2 years. These geometrical variables for the left and right side were recorded: diaphragmatic angle (LDA, RDA), diaphragmatic diameter (LDD, RDD), diaphragmatic height (LDH, RDH), diaphragmatic curvature index (LDCI, RDCI), lower lung diameter (LLLD, RLLD) and thoracic area (LTA, RTA). Results: It was demonstrated that the shape of the diaphragm in patients with large defects systematically differs from that of patients with small defects. Characteristically, patients with large defects present with a smaller LDCI (5.1 vs. 8.4, p < 0.001) at 6 months of age, which increases over time (11.4 vs. 7.0 at the age of 15.5 years, p = 0.727), representing a flattening of the patch and the attached rudimentary diaphragm as the child grows. Conclusions: Multiple variables during early follow-up were significantly associated with comorbidities such as recurrence, scoliotic curves of the spine and a reduced thoracic area. Some geometrical variables may serve as surrogate parameters for disease severity, which is associated with long-term comorbidities.
DOI:doi:10.3390/jcm13020620
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

kostenfrei: Volltext: https://doi.org/10.3390/jcm13020620
 kostenfrei: Volltext: https://www.mdpi.com/2077-0383/13/2/620
 DOI: https://doi.org/10.3390/jcm13020620
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:CDH
 chest radiographs
 comorbidities
 congenital diaphragmatic hernia
 long-term follow-up
 reconstructed diaphragm
 recurrence
K10plus-PPN:1905369301
Verknüpfungen:→ Zeitschrift

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