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Status: Bibliographieeintrag

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Verfasst von:Fritze, Stefan [VerfasserIn]   i
 Brandt, Geva A. [VerfasserIn]   i
 Benedyk, Anastasia [VerfasserIn]   i
 Moldavski, Alexander [VerfasserIn]   i
 Volkmer, Sebastian [VerfasserIn]   i
 Daub, Jonas [VerfasserIn]   i
 Krayem, Maria [VerfasserIn]   i
 Kukovic, Jacqueline [VerfasserIn]   i
 Schwarz, Emanuel [VerfasserIn]   i
 Braun, Urs [VerfasserIn]   i
 Wolf, Robert Christian [VerfasserIn]   i
 Kubera, Katharina Maria [VerfasserIn]   i
 Northoff, Georg [VerfasserIn]   i
 Meyer-Lindenberg, Andreas [VerfasserIn]   i
 Tost, Heike [VerfasserIn]   i
 Hirjak, Dusan [VerfasserIn]   i
Titel:Parkinsonism, psychomotor slowing, negative and depressive symptoms in schizophrenia spectrum and mood disorders
Titelzusatz:exploring their intricate nexus using a network analytic approach
Verf.angabe:Stefan Fritze, Geva A. Brandt, Anastasia Benedyk, Alexander Moldavski, Sebastian Volkmer, Jonas Daub, Maria Krayem, Jacqueline Kukovic, Emanuel Schwarz, Urs Braun, Robert Christian Wolf, Katharina M. Kubera, Georg Northoff, Andreas Meyer-Lindenberg, Heike Tost, and Dusan Hirjak
E-Jahr:2024
Jahr:26 April 2024
Umfang:15 S.
Illustrationen:Illustrationen
Fussnoten:Gesehen am 14.10.2024
Titel Quelle:Enthalten in: Schizophrenia bulletin
Ort Quelle:Oxford : Oxford Univ. Press, 1969
Jahr Quelle:2024
Band/Heft Quelle:(2024), Artikel-ID sbae055, Seite 1-15
ISSN Quelle:1745-1701
Abstract:Parkinsonism, psychomotor slowing, negative and depressive symptoms show evident phenomenological similarities across different mental disorders. However, the extent to which they interact with each other is currently unclear. Here, we hypothesized that parkinsonism is an independent motor abnormality showing limited associations with psychomotor slowing, negative and depressive symptoms in schizophrenia spectrum (SSD), and mood disorders (MOD).We applied network analysis and community detection methods to examine the interplay and centrality (expected influence [EI] and strength) between parkinsonism, psychomotor slowing, negative and depressive symptoms in 245 SSD and 99 MOD patients. Parkinsonism was assessed with the Simpson-Angus Scale (SAS). We used the Positive and Negative Syndrome Scale (PANSS) to examine psychomotor slowing (item #G7), negative symptoms (PANSS-N), and depressive symptoms (item #G6).In SSD and MOD, PANSS item #G7 and PANSS-N showed the largest EI and strength as measures of centrality. Parkinsonism had small or no influence on psychomotor slowing, negative and depressive symptoms in SSD and MOD. In SSD and MOD, exploratory graph analysis identified one community, but parkinsonism showed a small influence on its occurrence. Network Comparison Test yielded no significant differences between the SSD and MOD networks (global strength p value: .396 and omnibus tests p value: .574).The relationships between the individual domains followed a similar pattern in both SSD and MOD highlighting their transdiagnostic relevance. Despite evident phenomenological similarities, our results suggested that parkinsonism is more independent of negative and depressive symptoms than psychomotor slowing in both SSD and MOD.
DOI:doi:10.1093/schbul/sbae055
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1093/schbul/sbae055
 Volltext: https://academic.oup.com/schizophreniabulletin/advance-article/doi/10.1093/schbul/sbae055/7658525?login=true
 DOI: https://doi.org/10.1093/schbul/sbae055
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1905614586
Verknüpfungen:→ Zeitschrift

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