| |  Online-Ressource |
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| Verfasst von: | Xue, Can Can [VerfasserIn]  |
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| | Sim, Ralene [VerfasserIn] |
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| | Chee, Miao Li [VerfasserIn] |
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| | Yu, Marco [VerfasserIn] |
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| | Wang, Ya Xing [VerfasserIn] |
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| | Rim, Tyler Hyungtaek [VerfasserIn] |
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| | Hyung, Park Kyu [VerfasserIn] |
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| | Woong, Kang Se [VerfasserIn] |
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| | Song, Su Jeong [VerfasserIn] |
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| | Nangia, Vinay [VerfasserIn] |
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| | Panda-Jonas, Songhomitra [VerfasserIn] |
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| | Wang, Ning Li [VerfasserIn] |
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| | Hao, Jie [VerfasserIn] |
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| | Zhang, Qing [VerfasserIn] |
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| | Cao, Kai [VerfasserIn] |
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| | Sasaki, Mariko [VerfasserIn] |
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| | Harada, Sei [VerfasserIn] |
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| | Toru, Takebayashi [VerfasserIn] |
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| | Ryo, Kawasaki [VerfasserIn] |
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| | Raman, Rajiv [VerfasserIn] |
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| | Surya, Janani [VerfasserIn] |
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| | Khan, Rehana [VerfasserIn] |
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| | Bikbov, Mukharram [VerfasserIn] |
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| | Wong, Ian Y. [VerfasserIn] |
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| | Cheung, Chui Ming Gemmy [VerfasserIn] |
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| | Jonas, Jost B. [VerfasserIn] |
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| | Cheng, Ching-Yu [VerfasserIn] |
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| | Tham, Yih-Chung [VerfasserIn] |
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| Titel: | Is kidney function associated with age-related macular degeneration? |
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| Titelzusatz: | findings from the Asian Eye Epidemiology Consortium |
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| Verf.angabe: | Can Can Xue, PhD, Ralene Sim, MD, Miao Li Chee, BSc, Marco Yu, PhD, Ya Xing Wang, MD, Tyler Hyungtaek Rim, MD, PhD, Park Kyu Hyung, MD, PhD, Kang Se Woong, MD, PhD, Su Jeong Song, MD, Vinay Nangia, MD, PhD, Songhomitra Panda-Jonas, MD, Ning Li Wang, MD, PhD, Jie Hao, PhD, Qing Zhang, MD, Kai Cao, MD, Mariko Sasaki, MD, PhD, Sei Harada, MD, PhD, Takebayashi Toru, MD, PhD, Kawasaki Ryo, MD, PhD, Rajiv Raman, MS, Janani Surya, MSc, Rehana Khan, Mphil, Mukharram Bikbov, MD, PhD, Ian Y. Wong, FRCOphth, Chui Ming Gemmy Cheung, MD, PhD, Jost B. Jonas, MD, Ching-Yu Cheng, MD, PhD, Yih-Chung Tham, PhD |
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| E-Jahr: | 2024 |
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| Jahr: | June 2024 |
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| Umfang: | 8 S. |
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| Illustrationen: | Illustrationen |
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| Fussnoten: | Online verfügbar: 29. Dezember 2023, Artikelversion: 20. Mai 2024 ; Gesehen am 08.11.2024 |
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| Titel Quelle: | Enthalten in: Ophthalmology |
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| Ort Quelle: | Amsterdam [u.a.] : Elsevier, 1978 |
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| Jahr Quelle: | 2024 |
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| Band/Heft Quelle: | 131(2024), 6 vom: Juni, Seite 692-699 |
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| ISSN Quelle: | 1549-4713 |
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| Abstract: | Purpose - Chronic kidney disease (CKD) may elevate susceptibility to age-related macular degeneration (AMD) because of shared risk factors, pathogenic mechanisms, and genetic polymorphisms. Given the inconclusive findings in prior studies, we investigated this association using extensive datasets in the Asian Eye Epidemiology Consortium. - Design - Cross-sectional study. - Participants - Fifty-one thousand two hundred fifty-three participants from 10 distinct population-based Asian studies. - Methods - Age-related macular degeneration was defined using the Wisconsin Age-Related Maculopathy Grading System, the International Age-Related Maculopathy Epidemiological Study Group Classification, or the Beckman Clinical Classification. Chronic kidney disease was defined as estimated glomerular filtration rate (eGFR) of less than 60 ml/min per 1.73 m2. A pooled analysis using individual-level participant data was performed to examine the associations between CKD and eGFR with AMD (early and late), adjusting for age, sex, hypertension, diabetes, body mass index, smoking status, total cholesterol, and study groups. - Main Outcome Measures - Odds ratio (OR) of early and late AMD. - Results - Among 51 253 participants (mean age, 54.1 ± 14.5 years), 5079 had CKD (9.9%). The prevalence of early AMD was 9.0%, and that of late AMD was 0.71%. After adjusting for confounders, individuals with CKD were associated with higher odds of late AMD (OR, 1.46; 95% confidence interval [CI], 1.11-1.93; P = 0.008). Similarly, poorer kidney function (per 10-unit eGFR decrease) was associated with late AMD (OR, 1.12; 95% CI, 1.05-1.19; P = 0.001). Nevertheless, CKD and eGFR were not associated significantly with early AMD (all P ≥ 0.149). - Conclusions - Pooled analysis from 10 distinct Asian population-based studies revealed that CKD and compromised kidney function are associated significantly with late AMD. This finding further underscores the importance of ocular examinations in patients with CKD. - Financial Disclosure(s) - Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article. |
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| DOI: | doi:10.1016/j.ophtha.2023.12.030 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: https://doi.org/10.1016/j.ophtha.2023.12.030 |
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| | kostenfrei: Volltext: https://www.sciencedirect.com/science/article/pii/S0161642023009375 |
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| | DOI: https://doi.org/10.1016/j.ophtha.2023.12.030 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Age-related macular degeneration |
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| | Chronic kidney disease |
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| | Estimated glomerular filtration rate |
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| K10plus-PPN: | 1907994769 |
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| Verknüpfungen: | → Zeitschrift |
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Is kidney function associated with age-related macular degeneration? / Xue, Can Can [VerfasserIn]; June 2024 (Online-Ressource)
