The impact of Body Mass Index on the mortality of myocardial infarction patients with nonobstructive coronary arteries

• Verfasst von: Dong, Chaohui [VerfasserIn]
• Verfasst von: Kacmaz, Mustafa [VerfasserIn]
• Verfasst von: Schlettert, Clara [VerfasserIn]
• Verfasst von: Abumayyaleh, Mohammad S. A. [VerfasserIn]
• Verfasst von: Akın, Ibrahim [VerfasserIn]
• Verfasst von: Hemetsberger, Rayyan [VerfasserIn]
• Verfasst von: Mügge, Andreas [VerfasserIn]
• Verfasst von: Aweimer, Assem [VerfasserIn]
• Verfasst von: Hamdani, Nazha [VerfasserIn]
• Verfasst von: El-Battrawy, Ibrahim [VerfasserIn]
• Titel: The impact of Body Mass Index on the mortality of myocardial infarction patients with nonobstructive coronary arteries
• Verf.angabe: Chaohui Dong, Mustafa Kacmaz, Clara Schlettert, Mohammad Abumayyaleh, Ibrahim Akin, Rayyan Hemetsberger, Andreas Mügge, Assem Aweimer, Nazha Hamdani, Ibrahim El-Battrawy
• E-Jahr: 2024
• Jahr: September 2024
• Umfang: 10 S.
• Illustrationen: Illustrationen
• Fussnoten: Online veröffentlicht: 11. September 2024 ; Gesehen am 13.11.2024
• Titel Quelle: Enthalten in: Clinical cardiology
• Ort Quelle: Weinheim [u.a.] : Wiley, 1978
• Jahr Quelle: 2024
• Band/Heft Quelle: 47(2024), 9, Artikel-ID e70013, Seite 1-10
• ISSN Quelle: 1932-8737
• DOI: doi:10.1002/clc.70013
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: adverse events
• Sach-SW: mortality
• Sach-SW: myocardial infarction
• Sach-SW: obesity
• Sach-SW: overweight
• K10plus-PPN: 1908394781

Abstract

Objectives Myocardial infarction without significant stenosis or occlusion of the coronary arteries carries a high risk of recurrent major adverse cardiovascular events and poor prognosis. This study aimed to investigate the association between body mass index and outcomes in patients with a suspected myocardial infarction with nonobstructive coronary artery disease (MINOCA). Methods Patients were recruited at Bergmannsheil University Hospital from January 2010 to April 2021. The primary outcomes were in-hospital and long-term mortality. Secondary outcomes consisted of adverse events during hospitalization and during follow-up. Results A total of 373 patients were included in the study, with a mean follow-up time of 6.2 years. The patients were divided into different BMI groups: < 25 kg/m² (n = 121), 25−30 kg/m² (n = 140), and > 30 kg/m² (n = 112). In-hospital mortality was 1.7% versus 2.1% versus 4.5% (p = 0.368). However, long-term mortality tended to be higher in the < 25 kg/m² group compared to the 25−30 and > 30 kg/m² groups (log-rank p = 0.067). Subgroup analysis using Kaplan−Meier analysis showed a higher rate of cardiac cause of death in the < 25 kg/m² group compared to the 25−30 and > 30 kg/m² groups: 5.7% versus 1.1% versus 0.0% (log-rank p = 0.042). No significant differences were observed in other adverse events between the different BMI groups during hospitalization and long-term follow-up. Conclusions Patients with a BMI < 25 kg/m² who experience a suspected myocardial infarction without significant coronary artery disease may have higher all-cause mortality and cardiovascular cause of death. However, further data are needed to confirm these findings.