Specific chromatin states and m6A modifications are associated with mRNA mobility in planta

• Verfasst von: Liu, Xiaojun [VerfasserIn]
• Verfasst von: Uslu, Veli Vural [VerfasserIn]
• Verfasst von: Chen, Ying [VerfasserIn]
• Verfasst von: Han, Xiao [VerfasserIn]
• Verfasst von: Berr, Alexandre [VerfasserIn]
• Verfasst von: Zhang, Wenna [VerfasserIn]
• Verfasst von: Dong, Yihan [VerfasserIn]
• Titel: Specific chromatin states and m6A modifications are associated with mRNA mobility in planta
• Verf.angabe: Xiaojun Li, Veli Vural Uslu, Ying Chen, Xiao Han, Alexandre Berr, Wenna Zhang, and Yihan Dong
• E-Jahr: 2024
• Jahr: 8 April 2024
• Umfang: 4 S.
• Illustrationen: Illustrationen
• Fussnoten: Gesehen am 18.11.2024
• Titel Quelle: Enthalten in: Horticulture research
• Ort Quelle: Nanjing : Nanjing Agricultural Univ., 2014
• Jahr Quelle: 2024
• Band/Heft Quelle: 11(2024), 6 vom: Juni, Artikel-ID uhae101, Seite 1-4
• ISSN Quelle: 2052-7276
• DOI: doi:10.1093/hr/uhae101
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1908851392

Abstract

An alternative computational model suggests that mRNA mobility may primarily hinge on RNA abundance rather than sequence specificity [2]. Recent research provides an intriguing insight: m5C peaks tend to be concentrated in chromatin regions devoid of the repressive histone mark H3K27me3 [3]. This implies a positive association between m5C-modified mRNAs and active transcription. In an attempt to reconcile these divergent models, we have revisited experimental data on mobile mRNAs. Our findings suggest a refined perspective, indicating that mobile mRNAs are linked with specific chromatin states and predominantly associated with another RNA epigenetic mark, N6-methyladenosine (m6A) modifications.