A servo-control system for open- and closed-loop blood pressure regulation

• Verfasst von: Nafz, Benno [VerfasserIn]
• Verfasst von: Persson, Pontus B. [VerfasserIn]
• Verfasst von: Ehmke, Heimo [VerfasserIn]
• Verfasst von: Kirchheim, Hartmut [VerfasserIn]
• Titel: A servo-control system for open- and closed-loop blood pressure regulation
• Verf.angabe: B. Nafz, P.B. Persson, H. Ehmke, H.R. Kirchheim
• E-Jahr: 1992
• Jahr: February 1992
• Umfang: 6 S.
• Fussnoten: Gesehen am 25.11.2025
• Titel Quelle: Enthalten in: American journal of physiology. Renal physiology
• Ort Quelle: Bethesda, Md. : Soc., 1977
• Jahr Quelle: 1992
• Band/Heft Quelle: 262(1992), 2, Seite F320-F325
• ISSN Quelle: 1522-1466
• DOI: doi:10.1152/ajprenal.1992.262.2.F320
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1909464678

Abstract

An electropneumatic servo-control system is described that can reduce and control arterial blood pressure in experimental animals. The device has been proved useful in the analysis of pressure-dependent physiological processes and allows the following two modes of operation: 1) a conventional open-loop setting that will reduce arterial pressure to a preselected set point and 2) a closed-loop mode that enables an adjustment to a dynamic pressure set point (i.e., the controlled pressure is reduced to a constant value below a reference pressure). A pneumatic servo-control mechanism was chosen to provide minimal control latency. The accuracy of the system under physiological conditions is well within +/- 1 mmHg. The device can be useful in a number of studies demanding a precise regulation of local arterial pressure, such as experiments on blood flow autoregulation, arterial baroreceptor reflexes, and all experiments involving the study of pressure-dependent excretory and incretory functions of the kidney. The closed-loop setting is useful for studying physiological feedback systems.