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| Verfasst von: | Schilling, Danny [VerfasserIn]  |
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| | Ditrói, Tamás [VerfasserIn] |
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| | Barayeu, Uladzimir [VerfasserIn] |
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| | Jurányi, Eszter Petra [VerfasserIn] |
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| | Nagy, Peter [VerfasserIn] |
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| | Dick, Tobias P. [VerfasserIn] |
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| Titel: | The influence of alkylating agents on sulfur-sulfur bonds in per- and polysulfides |
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| Verf.angabe: | Danny Schilling, Tamás Ditrói, Uladzimir Barayeu, Eszter Petra Jurányi, Peter Nagy and Tobias P. Dick |
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| E-Jahr: | 2023 |
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| Jahr: | October 2023 |
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| Umfang: | 8 S. |
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| Fussnoten: | Gesehen am 10.12.2024 ; Available online 18 July 2023 |
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| Titel Quelle: | Enthalten in: Current opinion in chemical biology |
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| Ort Quelle: | Amsterdam : Elsevier, 1997 |
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| Jahr Quelle: | 2023 |
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| Band/Heft Quelle: | 76(2023) vom: Okt., Artikel-ID 102368, Seite 1-8 |
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| ISSN Quelle: | 1879-0402 |
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| Abstract: | Per- and polysulfides are sulfane sulfur species produced inside living cells, in organisms as diverse as bacteria, plants and humans, but their biological roles remain to be fully understood. Unfortunately, due to their reactivity, per- and polysulfides are easily altered, interconverted or lost during the processing and analysis of biological material. Thus, all current analytical methods make use of alkylating agents, to quench reactivity of hydropersulfides and hydropolysulfides and also to prevent free thiols from attacking sulfur chains in hydropolysulfides and dialkyl polysulfides. However, recent findings reveal that alkylating agents can also destroy per- and polysulfides, to varying degrees, depending on the choice of alkylating agent. Here, we discuss the challenges associated with the alkylation of per- and polysulfides, the single most important step for their preservation and detection in biological samples. |
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| DOI: | doi:10.1016/j.cbpa.2023.102368 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: https://doi.org/10.1016/j.cbpa.2023.102368 |
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| | kostenfrei: Volltext: https://www.sciencedirect.com/science/article/pii/S1367593123001060 |
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| | DOI: https://doi.org/10.1016/j.cbpa.2023.102368 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Alkylating agents |
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| | Dialkyl polysulfides |
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| | Hydropersulfides |
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| | Hydropolysulfides |
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| K10plus-PPN: | 1911808133 |
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| Verknüpfungen: | → Zeitschrift |
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¬The¬ influence of alkylating agents on sulfur-sulfur bonds in per- and polysulfides / Schilling, Danny [VerfasserIn]; October 2023 (Online-Ressource)
