Reactivation strength during cued recall is modulated by graph distance within cognitive maps

• Verfasst von: Kern, Simon [VerfasserIn]
• Verfasst von: Nagel, Juliane [VerfasserIn]
• Verfasst von: Gerchen, Martin Fungisai [VerfasserIn]
• Verfasst von: Gürsoy, Çağatay [VerfasserIn]
• Verfasst von: Meyer-Lindenberg, Andreas [VerfasserIn]
• Verfasst von: Kirsch, Peter [VerfasserIn]
• Verfasst von: Dolan, Raymond J [VerfasserIn]
• Verfasst von: Gais, Steffen [VerfasserIn]
• Verfasst von: Feld, Gordon Benedikt [VerfasserIn]
• Titel: Reactivation strength during cued recall is modulated by graph distance within cognitive maps
• Verf.angabe: Simon Kern, Juliane Nagel, Martin F Gerchen, Çağatay Gürsoy, Andreas Meyer-Lindenberg, Peter Kirsch, Raymond J Dolan, Steffen Gais, Gordon B Feld
• E-Jahr: 2024
• Jahr: May 29, 2024
• Umfang: 19 S.
• Illustrationen: Illustrationen
• Fussnoten: Gesehen am 11.12.2024
• Titel Quelle: Enthalten in: eLife
• Ort Quelle: Cambridge : eLife Sciences Publications, 2012
• Jahr Quelle: 2024
• Band/Heft Quelle: 12(2024), Artikel-ID RP93357, Seite 1-19
• ISSN Quelle: 2050-084X
• DOI: doi:10.7554/eLife.93357
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: brain decoding
• Sach-SW: MEG
• Sach-SW: memory reactivation
• Sach-SW: memory replay
• Sach-SW: retrieval
• K10plus-PPN: 1912043068

Abstract

Declarative memory retrieval is thought to involve reinstatement of neuronal activity patterns elicited and encoded during a prior learning episode. Furthermore, it is suggested that two mechanisms operate during reinstatement, dependent on task demands: individual memory items can be reactivated simultaneously as a clustered occurrence or, alternatively, replayed sequentially as temporally separate instances. In the current study, participants learned associations between images that were embedded in a directed graph network and retained this information over a brief 8 min consolidation period. During a subsequent cued recall session, participants retrieved the learned information while undergoing magnetoencephalographic recording. Using a trained stimulus decoder, we found evidence for clustered reactivation of learned material. Reactivation strength of individual items during clustered reactivation decreased as a function of increasing graph distance, an ordering present solely for successful retrieval but not for retrieval failure. In line with previous research, we found evidence that sequential replay was dependent on retrieval performance and was most evident in low performers. The results provide evidence for distinct performance-dependent retrieval mechanisms, with graded clustered reactivation emerging as a plausible mechanism to search within abstract cognitive maps.