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Verfasst von:Kampen, Michael van [VerfasserIn]   i
 Engenhart, Rita [VerfasserIn]   i
 Debus, Jürgen [VerfasserIn]   i
 Hess, Thomas [VerfasserIn]   i
 Schad, Lothar R. [VerfasserIn]   i
 Wannenmacher, Michael [VerfasserIn]   i
Titel:Low-grade astrocytoma
Titelzusatz:treatment with conventionally fractionated stereotactic radiation therapy.
Verf.angabe:M van Kampen, R Engenhart-Cabillic, J Debus, T Hess, L R Schad, M F Wannenmacher
Jahr:1996
Umfang:4 S.
Fussnoten:Gesehen am 17.12.2024
Titel Quelle:Enthalten in: Radiology
Ort Quelle:Oak Brook, Ill. : Soc., 1923
Jahr Quelle:1996
Band/Heft Quelle:201(1996), 1, Seite 275-278
ISSN Quelle:1527-1315
Abstract:PURPOSE: To assess the efficacy of fractionated stereotactic radiation therapy for low-grade astrocytoma in terms of improvements to therapeutic ratio, patient survival, and quality of life. MATERIALS AND METHODS: Since 1987, 32 patients with inoperable grade II astrocytoma were irradiated. Stereotactic radiation therapy was given only to patients with progressive symptoms. The mean total dose applied was 59.8 Gy (range, 54.0-65.0 Gy). RESULTS: Four years after therapy, the overall survival rate calculated with Kaplan-Meier analysis was 76%. Median progression-free survival was 48 months. On the basis of clinical symptoms, 91% (29 of 32) of patients showed improvement or stable disease after stereotactic radiation therapy. Eleven local failures were observed, 10 of which were within the planning target volume; one patient had a continuously enlarging mass. Acute toxic effects of radiation did not exceed grade II of the World Health Organization classification. Two patients developed reversible contrast enhancement without clinical symptoms on MR images within 1 year after stereotactic radiation therapy. CONCLUSION: Stereotactic radiation therapy for grade II astrocytoma appears to improve patients' quality of life or stabilize disease and is not correlated with marginal misses.
DOI:doi:10.1148/radiology.201.1.8816559
URL:Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.

Volltext: https://doi.org/10.1148/radiology.201.1.8816559
 Volltext: https://pubs.rsna.org/doi/10.1148/radiology.201.1.8816559
 DOI: https://doi.org/10.1148/radiology.201.1.8816559
Datenträger:Online-Ressource
Sprache:eng
K10plus-PPN:1912809338
Verknüpfungen:→ Zeitschrift

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