Severe Combined Immunodeficiency

• Titel: Severe Combined Immunodeficiency
• Mitwirkende: D'Elios, Mario Milco [HerausgeberIn]
• Verf.angabe: edited by Mario Milco D'Elios
• Ausgabe: 1st ed. 2024.
• Verlagsort: Cham
• Verlagsort: Cham
• Verlag: Springer Nature Switzerland
• Verlag: Imprint: Springer
• E-Jahr: 2024
• Jahr: 2024.
• Jahr: 2024.
• Umfang: 1 Online-Ressource(IX, 121 p. 12 illus. in color.)
• Gesamttitel/Reihe: Rare Diseases of the Immune System
• ISBN: 978-3-031-78864-2
• DOI: doi:10.1007/978-3-031-78864-2
• Datenträger: Online-Ressource
• Sprache: eng
• Bibliogr. Hinweis: Erscheint auch als : Druck-Ausgabe
• Bibliogr. Hinweis: Erscheint auch als : Druck-Ausgabe
• Bibliogr. Hinweis: Erscheint auch als : Druck-Ausgabe
• K10plus-PPN: 1913280918
• K10plus-PPN:
  Universitätsbibliothek
• Lokale URL UB: Zum Volltext
• Lokale URL UB: Bibliothek der Medizinischen Fakultät Mannheim der Universität Heidelberg
• Bibliothek/Idn: UW / m4639787235
• Lokale URL Inst.: Zum Volltext

Abstract

Preface -- 1. Mucosal Immunity in Primary Immunodeficiencies -- 2. Genetic defects associated with SCID and their impact on lymphocyte development -- 3. Bioinformatics in primary immunodeficiencies: Towards a "computational immunology" era -- 4. Clinical management of severe combined immunodeficiencies -- 5. Hot topics in SCID -- 6. Late-onset and hypomorphic presentation of severe combined immune deficiency -- 7. Gut involvement in Cellular Immunodeficiencies -- Subject index.

Abstract

This handy volume, that can also serve as an integration to the preceding work Cellular Primary Immunodeficiencies by the same editor, presents detailed state of the art knowledge on Severe Combined Immunodeficiency (SCID) with extensive coverage of both basic science discoveries and the latest clinical advances in the field. The book is structured according to the most recent classifications including update on the immunological synapse, as well as on bioinformatics in primary immunodeficiencies leading the reader towards the computational immunology era. Readers will also find in-depth descriptions of SCID genes and related clinical application, and aspects such as differential diagnosis, clinical management, and the role of vaccines are also addressed. The authors are recognized experts world-wide and have crafted their chapters to turn Severe Combined Immunodeficiency in a valued, compact update for immunologists, paediatricians, internists, rheumatologists, and infectious diseases specialists, that MDs and PhD students will find informative as well.